EP 4153569 A1 20230329 - PROCESS OF PREPARING BUTYL-(5S)-5-({2-[4-(BUTOXYCARBONYL)PHENYL]ETHYL}[2-(2-{[3-CHLORO-4'-(TRIFLUOROMETHYL)[BIPHENYL]-4-YL]METHOXY}PHENYL)ETHYL]AMINO)-5,6,7,8-TETRAHYDROQUINOLINE-2-CARBOXYLATE
Title (en)
PROCESS OF PREPARING BUTYL-(5S)-5-({2-[4-(BUTOXYCARBONYL)PHENYL]ETHYL}[2-(2-{[3-CHLORO-4'-(TRIFLUOROMETHYL)[BIPHENYL]-4-YL]METHOXY}PHENYL)ETHYL]AMINO)-5,6,7,8-TETRAHYDROQUINOLINE-2-CARBOXYLATE
Title (de)
VERFAHREN ZUR HERSTELLUNG VON BUTYL-(5S)-5-({2-[4-(BUTOXYCARBONYL)PHENYL]ETHYL}[2-(2-{[3-CHLOR-4'-(TRIFLUORMETHYL)[BIPHENYL]-4-YL]METHOXY}PHENYL)ETHYL]AMINO)-5,6,7,8-TETRAHYDROCHINOLIN-2-CARBOXYLAT
Title (fr)
PROCÉDÉ DE PRÉPARATION DE BUTYL-(5S)-5-({2-[4-(BUTOXYCARBONYL)PHÉNYL]ÉTHYL}[2-(2-{[3-CHLORO-4'-(TRIFLUOROMÉTHYL)[BIPHÉNYLE]-4-YL]MÉTHOXY}PHÉNYL)ÉTHYL]AMINO)-5,6,7,8-TÉTRAHYDROQUINOLÉINE-2-CARBOXYLATE
Publication
Application
Priority
- EP 20175721 A 20200520
- EP 2021062837 W 20210514
Abstract (en)
[origin: WO2021233783A1] The invention relates to a new and improved process of preparing butyl-(5S)-5-({2-[4-(butoxycarbonyl)phenyl]ethyl}[2-(2-{[3-chloro-4'-(trifluoromethyl)[biphenyl]-4-yl]methoxy}phenyl)ethyl]amino)-5,6,7,8-tetrahydroquinoline-2-carboxylate of formula (XII), new precursors for its preparation, and to its use for preparing (5S)-5-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4'-(trifluoromethyl)[biphenyl]-4-yl]methoxy}phenyl)ethyl]amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid.
IPC 8 full level
C07D 217/26 (2006.01)
CPC (source: EP IL KR US)
C07D 215/48 (2013.01 - KR); C07D 217/26 (2013.01 - EP IL); C07D 221/04 (2013.01 - US); Y02P 20/55 (2015.11 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021233783 A1 20211125; AR 122140 A1 20220817; AU 2021276066 A1 20221208; BR 112022020799 A2 20221129; CA 3183771 A1 20211125; CL 2022003220 A1 20230310; CN 115803318 A 20230314; EP 4153569 A1 20230329; IL 298316 A 20230101; JP 2023526402 A 20230621; KR 20230012494 A 20230126; MX 2022014655 A 20221215; TW 202202140 A 20220116; US 2023183181 A1 20230615
DOCDB simple family (application)
EP 2021062837 W 20210514; AR P210101384 A 20210520; AU 2021276066 A 20210514; BR 112022020799 A 20210514; CA 3183771 A 20210514; CL 2022003220 A 20221117; CN 202180036114 A 20210514; EP 21724712 A 20210514; IL 29831622 A 20221116; JP 2022570363 A 20210514; KR 20227040060 A 20210514; MX 2022014655 A 20210514; TW 110117776 A 20210517; US 202117999179 A 20210514