EP 4157204 A1 20230405 - DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC
Title (en)
DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC
Title (de)
DIHOMO-GAMMA LINOLENSÄURE (DGLA) IST EIN SENOLYTISCHES MITTEL
Title (fr)
ACIDE DIHOMO-GAMMA-LINOLÉNIQUE (DGLA) COMME NOUVEL AGENT SÉNOLYTIQUE
Publication
Application
Priority
- US 202063033739 P 20200602
- US 202163148094 P 20210210
- US 2021035271 W 20210601
Abstract (en)
[origin: WO2021247594A1] Methods are provided that relate to the discovery that dihomo-gamma linolenic acid (DGLA) is a potent senolytic agent. Accordingly, in certain embodiments, methods of selectively killing one or more senescent cells in a subject in need thereof are provided wherein the method(s) involves administering to the subject an effective amount of DGLA.
IPC 8 full level
A61K 8/30 (2006.01); A61K 31/201 (2006.01); A61K 31/202 (2006.01); A61P 17/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP US)
A61K 8/361 (2013.01 - EP); A61K 8/411 (2013.01 - EP); A61K 31/136 (2013.01 - EP); A61K 31/201 (2013.01 - EP); A61K 31/202 (2013.01 - EP US); A61K 31/232 (2013.01 - EP); A61K 31/519 (2013.01 - EP); A61K 31/55 (2013.01 - EP); A61K 45/06 (2013.01 - EP US); A61P 17/00 (2018.01 - EP); A61P 29/00 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61Q 19/08 (2013.01 - EP); A61K 2800/782 (2013.01 - EP)
C-Set (source: EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021247594 A1 20211209; AU 2021283886 A1 20230119; CA 3181134 A1 20211209; EP 4157204 A1 20230405; US 2024216316 A1 20240704
DOCDB simple family (application)
US 2021035271 W 20210601; AU 2021283886 A 20210601; CA 3181134 A 20210601; EP 21816897 A 20210601; US 202118008135 A 20210601