EP 4164690 A1 20230419 - SMALL MOLECULE VE-PTP INHIBITORS
Title (en)
SMALL MOLECULE VE-PTP INHIBITORS
Title (de)
KLEINMOLEKÜLIGE VE-PTP-HEMMER
Title (fr)
INHIBITEURS DE VE-PTP À PETITES MOLÉCULES
Publication
Application
Priority
- US 202063039764 P 20200616
- US 2021037714 W 20210616
Abstract (en)
[origin: WO2021257754A1] The present disclosure relates to compounds capable of inhibiting vascular endothelial protein tyrosine phosphatase (VE-PTP). These compounds are also capable of activating Tie2 receptor-mediated signaling. The present disclosure also relates to pharmaceutically acceptable salts of said compounds, to pharmaceutical compositions comprising such compounds and/or pharmaceutically acceptable salts thereof, and to the use of such compounds, pharmaceutically acceptable salts thereof, and/or pharmaceutical compositions comprising the same in treating diseases and/or conditions mediated by VE-PTP signaling, such as those mediated by Angiopoietm/Tie2 signaling.
IPC 8 full level
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C12N 15/13 (2006.01)
CPC (source: EP)
A61P 9/00 (2018.01); A61P 27/06 (2018.01); C07D 277/28 (2013.01); C07D 401/04 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021257754 A1 20211223; AU 2021292526 A1 20230216; CA 3182748 A1 20211223; CN 117460743 A 20240126; EP 4164690 A1 20230419; JP 2023530457 A 20230718
DOCDB simple family (application)
US 2021037714 W 20210616; AU 2021292526 A 20210616; CA 3182748 A 20210616; CN 202180050398 A 20210616; EP 21825008 A 20210616; JP 2022577587 A 20210616