EP 4168534 A1 20230426 - PROCESS FOR PRODUCING CARRIER PARTICLES FOR THE CULTIVATION OF BIOLOGICAL CELLS, CARRIER PARTICLES AND THEIR USE
Title (en)
PROCESS FOR PRODUCING CARRIER PARTICLES FOR THE CULTIVATION OF BIOLOGICAL CELLS, CARRIER PARTICLES AND THEIR USE
Title (de)
VERFAHREN ZUR HERSTELLUNG VON TRÄGERPARTIKELN FÜR DIE KULTIVIERUNG BIOLOGISCHER ZELLEN, TRÄGERPARTIKEL UND DEREN ANWENDUNG
Title (fr)
PROCÉDÉ DE PRODUCTION DE PARTICULES PORTEUSES POUR LA CULTURE DE CELLULES BIOLOGIQUES, PARTICULES PORTEUSES ET LEUR UTILISATION
Publication
Application
Priority
- DE 102020116108 A 20200618
- EP 2021066071 W 20210615
Abstract (en)
[origin: WO2021255008A1] The invention relates to a process for producing carrier particles for the cultivation of biological cells, comprising the steps of providing an aqueous suspension of hydrogel beads and freeze-drying of the hydrogel beads so that dry hydrogel particles are formed, wherein at least one lyoprotectant substance is added to the suspension, the hydrogel beads are loaded in the suspension with the lyoprotectant substance and the dry hydrogel particles receive a shape under the effect of the lyoprotectant substance, which shape approximates a spherical particle shape and is still maintained after rehydrating. The invention also relates to carrier particles for a cultivation of biological cells, which comprise dry hydrogel particles, preferably having a protein coating, and to applications of the carrier particles.
IPC 8 full level
C12N 5/00 (2006.01)
CPC (source: EP KR US)
C12N 5/0075 (2013.01 - EP KR US); C12N 2531/00 (2013.01 - EP KR US); C12N 2533/20 (2013.01 - US); C12N 2533/52 (2013.01 - KR); C12N 2533/54 (2013.01 - KR); C12N 2533/74 (2013.01 - EP KR US); C12N 2537/10 (2013.01 - US)
Citation (search report)
See references of WO 2021255008A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
DE 102020116108 A1 20211223; CL 2022003614 A1 20230630; CN 115885034 A 20230331; EP 4168534 A1 20230426; JP 2023531633 A 20230725; KR 20230027159 A 20230227; US 2023272338 A1 20230831; WO 2021255008 A1 20211223
DOCDB simple family (application)
DE 102020116108 A 20200618; CL 2022003614 A 20221215; CN 202180042487 A 20210615; EP 2021066071 W 20210615; EP 21733774 A 20210615; JP 2022577614 A 20210615; KR 20237001167 A 20210615; US 202118009071 A 20210615