EP 4171553 A1 20230503 - MMP-9 AND MMP-12 INHIBITION FOR TREATING SPINAL CORD INJURY OR RELATED INJURY TO NEUROLOGICAL TISSUE
Title (en)
MMP-9 AND MMP-12 INHIBITION FOR TREATING SPINAL CORD INJURY OR RELATED INJURY TO NEUROLOGICAL TISSUE
Title (de)
MMP-9- UND MMP-12-HEMMUNG ZUR BEHANDLUNG VON RÜCKENMARKSVERLETZUNGEN ODER VERWANDTEN VERLETZUNGEN VON NEUROLOGISCHEM GEWEBE
Title (fr)
INHIBITION DE MMP-9 ET MMP-12 POUR LE TRAITEMENT D'UNE LÉSION DE LA MOELLE ÉPINIÈRE OU D'UNE LÉSION ASSOCIÉE À UN TISSU NEUROLOGIQUE
Publication
Application
Priority
- US 202063044496 P 20200626
- GB 2021051616 W 20210625
Abstract (en)
[origin: WO2021260387A1] The use of a single compound or a combination of compounds which selectively inhibit both matrix metalloproteinases MMP-9 and MMP-12 in treating spinal cord injury (SCI), the secondary effects of SCI and related injury to neurological tissue are described, in particular the suppression of SCI- induced oedema, treatment of neuropathic pain, the prevention of functional decline following SCI and methods of administration.
IPC 8 full level
A61K 31/426 (2006.01); A61K 31/4439 (2006.01); A61K 45/00 (2006.01); A61K 45/06 (2006.01); A61P 25/00 (2006.01)
CPC (source: EP US)
A61K 31/426 (2013.01 - EP US); A61K 31/4439 (2013.01 - EP US); A61K 45/06 (2013.01 - EP); A61P 25/00 (2017.12 - EP US)
Citation (search report)
See references of WO 2021260387A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021260387 A1 20211230; CN 116033902 A 20230428; EP 4171553 A1 20230503; JP 2023533462 A 20230803; US 2023255943 A1 20230817
DOCDB simple family (application)
GB 2021051616 W 20210625; CN 202180050038 A 20210625; EP 21739754 A 20210625; JP 2022580174 A 20210625; US 202118012561 A 20210625