EP 4179081 A1 20230517 - ALGINATE BEADS AND PRODUCTION THEREOF
Title (en)
ALGINATE BEADS AND PRODUCTION THEREOF
Title (de)
ALGINATPERLEN UND DEREN HERSTELLUNG
Title (fr)
BILLES D'ALGINATE ET LEUR PRODUCTION
Publication
Application
Priority
- EP 20185532 A 20200713
- EP 2021069527 W 20210713
Abstract (en)
[origin: EP3940072A1] The present invention aims to solve the problem by providing methods for producing solid, hollow and 2-layer alginate beads, wherein the alginate solidifies via slow release of divalent ions into an alginate solution. It is here provided a solution that allows a slow release of divalent cations into an alginate solution leading to solidification of the solution and formation of homogeneous beads, hollow beads or 2-layer beads. This invention also improves the viability of cells and microorganisms compared to other slow divalent cation release techniques to produce alginate beads or capsules.Further, it provides a use of the methods for producing solid, hollow and 2-layer alginate beads for co-culturing fluorescent reporter cell-lines and microorganisms, wherein the fluorescent reporter cell-lines and the microorganisms are co-encapsulated into the core or shell of the alginate beads.
IPC 8 full level
C12N 11/04 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 9/50 (2006.01); C12N 1/04 (2006.01); C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12N 11/10 (2006.01); G01N 21/64 (2006.01)
CPC (source: EP)
A61K 9/1652 (2013.01); A61K 9/1694 (2013.01); A61K 9/5036 (2013.01); A61K 9/5089 (2013.01); C12N 1/04 (2013.01); C12N 5/0012 (2013.01); C12N 11/04 (2013.01); C12N 11/10 (2013.01); C12N 2533/74 (2013.01)
Citation (search report)
See references of WO 2022013254A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
EP 3940072 A1 20220119; EP 4179081 A1 20230517; WO 2022013254 A1 20220120
DOCDB simple family (application)
EP 20185532 A 20200713; EP 2021069527 W 20210713; EP 21742832 A 20210713