EP 4182028 A1 20230524 - COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY
Title (en)
COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY
Title (de)
VERBINDUNGEN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON ERKRANKUNGEN IM ZUSAMMENHANG MIT STING-AKTIVITÄT
Title (fr)
COMPOSÉS ET COMPOSITIONS POUR LE TRAITEMENT DES ÉTATS ASSOCIÉS À UNE ACTIVITÉ DE STING
Publication
Application
Priority
- US 202063052117 P 20200715
- US 2021041792 W 20210715
Abstract (en)
[origin: WO2022015957A1] This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.
IPC 8 full level
A61P 35/00 (2006.01); A61K 31/4427 (2006.01); A61K 31/4439 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP)
A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2022015957 A1 20220120; AR 122976 A1 20221019; CN 116528862 A 20230801; EP 4182028 A1 20230524; JP 2023540672 A 20230926; TW 202216685 A 20220501; UY 39328 A 20220131
DOCDB simple family (application)
US 2021041792 W 20210715; AR P210101985 A 20210715; CN 202180063054 A 20210715; EP 21751933 A 20210715; JP 2023502898 A 20210715; TW 110125785 A 20210714; UY 39328 A 20210715