EP 4183786 A1 20230524 - DERIVATIVES OF QUINOLINES AS INHIBITORS OF DYRK1A AND/OR DYRK1B KINASES
Title (en)
DERIVATIVES OF QUINOLINES AS INHIBITORS OF DYRK1A AND/OR DYRK1B KINASES
Title (de)
CHINOLINDERIVATE ALS INHIBITOREN VON DYRK1A- UND/ODER DYRK1B-KINASEN
Title (fr)
DÉRIVÉS DE QUINOLÉINES EN TANT QU'INHIBITEURS DE KINASES DYRK1A ET/OU DYRK1B
Publication
Application
Priority
- EP 16460096 A 20161223
- EP 17883520 A 20171220
- US 2017067527 W 20171220
Abstract (en)
The present invention relates to the compound of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof. The present invention is further concerned with the use of such a compound or salt, stereoisomer, tautomer or N-oxide thereof as medicament and a pharmaceutical composition comprising said compound.
IPC 8 full level
C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61K 31/47 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP US)
A61P 35/00 (2018.01 - EP US); C07D 471/04 (2013.01 - EP US); C07D 519/00 (2013.01 - EP US)
Citation (applicant)
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Citation (search report)
- [X] WO 2005095400 A1 20051013 - VERTEX PHARMA [US], et al
- [A] WO 2013026806 A1 20130228 - EXONHIT SA [FR], et al
- [A] WO 2016000615 A1 20160107 - SUNSHINE LAKE PHARMA CO LTD [CN]
- [AD] WO 2012098068 A1 20120726 - HOFFMANN LA ROCHE [CH], et al
- [T] YOSHIDA KIYOTSUGU ED - POIROT MARC ET AL: "Role for DYRK family kinases on regulation of apoptosis", BIOCHEMICAL PHARMACOLOGY, vol. 76, no. 11, 20 December 2008 (2008-12-20), pages 1389 - 1394, XP029293024, ISSN: 0006-2952, DOI: 10.1016/J.BCP.2008.05.021
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 10577365 B2 20200303; US 2018179199 A1 20180628; EP 3558321 A1 20191030; EP 3558321 A4 20200527; EP 3558321 B1 20230201; EP 4183786 A1 20230524; JP 2020502252 A 20200123; JP 2022166286 A 20221101; JP 7134973 B2 20220912; LT 3558321 T 20230510; PL 3558321 T3 20231023; WO 2018119039 A1 20180628
DOCDB simple family (application)
US 201715848786 A 20171220; EP 17883520 A 20171220; EP 22214338 A 20171220; JP 2019534721 A 20171220; JP 2022133200 A 20220824; LT 17067527 T 20171220; PL 17883520 T 20171220; US 2017067527 W 20171220