EP 4185866 A1 20230531 - A SCREENING METHOD FOR DIAGNOSING GROWTH HORMONE DEFICIENCY IN PEDIATRIC PATIENTS BY USING MACIMORELIN
Title (en)
A SCREENING METHOD FOR DIAGNOSING GROWTH HORMONE DEFICIENCY IN PEDIATRIC PATIENTS BY USING MACIMORELIN
Title (de)
SCREENING-VERFAHREN ZUR DIAGNOSE VON WACHSTUMSHORMONMANGEL BEI PÄDIATRISCHEN PATIENTEN UNTER VERWENDUNG VON MACIMORELIN
Title (fr)
MÉTHODE DE CRIBLAGE PERMETTANT LE DIAGNOSTIC D'UNE DÉFICIENCE EN HORMONE DE CROISSANCE CHEZ DES PATIENTS PÉDIATRIQUES À L'AIDE DE LA MACIMORÉLINE
Publication
Application
Priority
EP 2020070691 W 20200722
Abstract (en)
[origin: WO2022017599A1] The present invention relates to a screening method for diagnosing growth hormone deficiency in pediatric patients by using macimorelin. The present invention further provides the substance macimorelin for use in diagnosing growth hormone deficiency in pediatric patients. The method comprises providing at least one blood sample, taken from a subject within a range from about 15 to about 100 minutes following an administration of an amount of macimorelin effective for inducing growth hormone secretion, measuring the growth hormone level of each blood sample, comparing the measured growth hormone level with a single threshold value, diagnosing whether the subject suffers from growth hormone deficiency or not based on the comparison of growth hormone level with said single threshold value in said at least one blood sample. The method of the invention is a stand-alone test and does not need to be repeated and no alternative growth hormone stimulation test is required to reliably diagnose pediatric patients.
IPC 8 full level
G01N 33/50 (2006.01); G01N 33/74 (2006.01)
CPC (source: CN EP IL KR)
G01N 33/5091 (2013.01 - EP IL); G01N 33/74 (2013.01 - CN EP IL KR); G01N 2333/61 (2013.01 - CN)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2022017599 A1 20220127; AR 124626 A1 20230419; AU 2020460118 A1 20230202; CA 3185680 A1 20220127; CN 114258492 A 20220329; EP 4185866 A1 20230531; IL 299918 A 20230301; JP 2023535000 A 20230815; KR 102635025 B1 20240207; KR 20220015466 A 20220208; MX 2023000935 A 20230222; TW 202219511 A 20220516
DOCDB simple family (application)
EP 2020070691 W 20200722; AR P210102035 A 20210720; AU 2020460118 A 20200722; CA 3185680 A 20200722; CN 202080006891 A 20200722; EP 20745175 A 20200722; IL 29991823 A 20230115; JP 2023504173 A 20200722; KR 20217043189 A 20200722; MX 2023000935 A 20200722; TW 110122905 A 20210623