Global Patent Index - EP 4210551 A2

EP 4210551 A2 20230719 - FLUORESCENT REPORTER AND USE THEREOF FOR THE DETECTION OF TARGET MOLECULES

Title (en)

FLUORESCENT REPORTER AND USE THEREOF FOR THE DETECTION OF TARGET MOLECULES

Title (de)

FLUORESZIERENDE REPORTER UND DEREN VERWENDUNG ZUM NACHWEIS VON ZIELMOLEKÜLEN

Title (fr)

RAPPORTEUR FLUORESCENT ET SON UTILISATION POUR LA DÉTECTION DE MOLÉCULES CIBLES

Publication

EP 4210551 A2 20230719 (FR)

Application

EP 21811112 A 20210910

Priority

  • FR 2009245 A 20200911
  • FR 2021051554 W 20210910

Abstract (en)

[origin: WO2022053769A2] The invention relates to a device for detecting a target molecule (2) and/or measuring the concentration of a target molecule (2) comprising: a substrate at the surface of which is covalently attached a grafting molecule; at least one fluorescent probe (1) comprising: at least one receptor (11) bonded to a polypeptide (12) via a covalent bond; two fluorochromes Fa and Fb; in which the fluorochrome Fa is bonded to the receptor (11) and the fluorochrome Fb is bonded to the polypeptide (12); and the fluorochromes Fa and Fb form a FRET donor/acceptor pair; in which the polypeptide (12) is bonded to the grafting molecule via a covalent bond. The invention also relates to a fluorescent probe and a method for detecting a target molecule and/or measuring the concentration of a target molecule.

IPC 8 full level

A61B 1/00 (2006.01); G01N 21/64 (2006.01); G01N 33/542 (2006.01)

CPC (source: EP US)

A61B 5/0071 (2013.01 - EP); G01N 21/6428 (2013.01 - EP US); G01N 33/542 (2013.01 - EP); G01N 33/582 (2013.01 - US); G01N 33/6803 (2013.01 - US); G01N 2021/6441 (2013.01 - EP)

Citation (search report)

See references of WO 2022053769A2

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

Designated validation state (EPC)

KH MA MD TN

DOCDB simple family (publication)

FR 3114160 A1 20220318; EP 4210551 A2 20230719; JP 2023542305 A 20231006; US 2023349910 A1 20231102; WO 2022053769 A2 20220317; WO 2022053769 A3 20220505

DOCDB simple family (application)

FR 2009245 A 20200911; EP 21811112 A 20210910; FR 2021051554 W 20210910; JP 2023516528 A 20210910; US 202118044833 A 20210910