EP 4228636 A1 20230823 - COMPOSITIONS AND METHODS FOR STORAGE STABLE OPHTHALMIC DRUGS
Title (en)
COMPOSITIONS AND METHODS FOR STORAGE STABLE OPHTHALMIC DRUGS
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN FÜR LAGERSTABILE OPHTHALMISCHE ARZNEIMITTEL
Title (fr)
COMPOSITIONS ET PROCÉDÉS POUR DES MÉDICAMENTS OPHTALMIQUES STABLES AU STOCKAGE
Publication
Application
Priority
- US 202017069155 A 20201013
- US 2021029536 W 20210428
Abstract (en)
[origin: WO2022081204A1] The present invention is related to methods of stabilizing an ophthalmic drug by adding a surfactant and a viscosity enhancer to the ophthalmic drug to create a composition wherein the composition has a viscosity of about 25 centipoise or less at a shear rate of 1/1000 per second at 25 degrees Celsius and a viscosity of about 70 centipoise or more at shear rate of 1 per second at 25 degrees Celsius, filling the composition into a container; and storing the container at a temperature from about 2 degrees Celsius to about 25 degrees Celsius, The present invention is further directed to a container prepared by the methods of the present invention.
IPC 8 full level
A61K 31/439 (2006.01); A61K 31/4409 (2006.01); A61K 47/10 (2017.01)
CPC (source: EP KR)
A61K 9/0048 (2013.01 - EP KR); A61K 9/08 (2013.01 - EP KR); A61K 31/439 (2013.01 - EP KR); A61K 31/5575 (2013.01 - EP KR); A61K 47/02 (2013.01 - EP); A61K 47/10 (2013.01 - EP KR); A61K 47/38 (2013.01 - KR); A61P 27/02 (2018.01 - KR); A61P 27/06 (2018.01 - KR); A61K 9/19 (2013.01 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2022081204 A1 20220421; AU 2021361731 A1 20230525; CA 3195422 A1 20220421; CN 116847841 A 20231003; EP 4228636 A1 20230823; JP 2023544918 A 20231025; KR 20230131822 A 20230914; MX 2023004298 A 20230809
DOCDB simple family (application)
US 2021029536 W 20210428; AU 2021361731 A 20210428; CA 3195422 A 20210428; CN 202180081410 A 20210428; EP 21880707 A 20210428; JP 2023547174 A 20210428; KR 20237016074 A 20210428; MX 2023004298 A 20210428