EP 4237000 A4 20240918 - TWO-DOMAIN MULTIMERIC FUSION PROTEINS
Title (en)
TWO-DOMAIN MULTIMERIC FUSION PROTEINS
Title (de)
MULTIMERE FUSIONSPROTEINE MIT ZWEI DOMÄNEN
Title (fr)
PROTÉINES DE FUSION MULTIMÈRES À DEUX DOMAINES
Publication
Application
Priority
- US 202063108789 P 20201102
- US 202163246247 P 20210920
- US 202163253501 P 20211007
- US 2021057777 W 20211102
Abstract (en)
[origin: WO2022094482A1] Provided are conjugates of TRAIL and another Tumor Necrosis Factor (TNF) superfamily ligand, and related compositions and methods of use thereof. Also provided are conjugates of two trimeric polypeptides linked through a genetically encoded linker or chemical linkers and related compositions and methods of use thereof.
IPC 8 full level
A61K 39/39 (2006.01); A61P 37/04 (2006.01); C07K 14/435 (2006.01); C07K 14/52 (2006.01); C07K 14/525 (2006.01); C07K 14/705 (2006.01)
CPC (source: EP)
A61P 37/04 (2018.01); C07K 14/70575 (2013.01); C07K 14/70578 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01)
Citation (search report)
- [Y] WO 2010105068 A1 20100916 - UNIV PENNSYLVANIA [US], et al
- [Y] WO 2018157162 A1 20180830 - SHATTUCK LABS INC [US]
- [Y] WO 2017059168 A1 20170406 - HEAT BIOLOGICS INC [US]
- [A] US 2018346549 A1 20181206 - LIANG PENG [US]
- [A] WO 2017167672 A1 20171005 - HOFFMANN LA ROCHE [CH], et al
- [IY] EDWIN BREMER: "Targeting of the Tumor Necrosis Factor Receptor Superfamily for Cancer Immunotherapy", ISRN ONCOLOGY, vol. 2013, 1 June 2013 (2013-06-01), pages 1 - 25, XP055360248, ISSN: 2356-7872, DOI: 10.1155/2013/371854
- See also references of WO 2022094482A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2022094482 A1 20220505; EP 4237000 A1 20230906; EP 4237000 A4 20240918
DOCDB simple family (application)
US 2021057777 W 20211102; EP 21887783 A 20211102