EP 4237868 B1 20240221 - DETERMINATION OF A SUBJECT SPECIFIC HEMODYNAMIC RESPONSE FUNCTION
Title (en)
DETERMINATION OF A SUBJECT SPECIFIC HEMODYNAMIC RESPONSE FUNCTION
Title (de)
BESTIMMUNG EINER SUBJEKTSPEZIFISCHEN HÄMODYNAMISCHEN ANTWORTFUNKTION
Title (fr)
DÉTERMINATION D'UNE FONCTION DE RÉPONSE HÉMODYNAMIQUE SPÉCIFIQUE À UN SUJET
Publication
Application
Priority
- EP 21197367 A 20210917
- EP 2022074297 W 20220901
Abstract (en)
[origin: EP4152032A1] Disclosed herein is a medical system (100, 300) where execution of machine executable instructions (120) causes a computational system (104) to: receive (200) a time series of a R2-star map (122) for a brain volume (500); receive (202) a stimulus signal (124) descriptive of an occurrence of a sensory stimulus; receive (204) a selection of one or more seed voxels (126) identified in the time series of the R2-star map; calculate (206) a denoised time series of the R2-star map (128); calculate (208) a correlation map (130) between the seed voxels and the denoised time series of the R2-star map; determine (210) an activated region (132) of the brain volume using voxels identified in the correlation map; provide (212) a hemodynamic response (134) function for each voxel and each occurrence of the sensory stimulus; and provide (214) a subject specific hemodynamic response function (136) by averaging the hemodynamic response functions.
IPC 8 full level
G01R 33/48 (2006.01); A61B 5/00 (2006.01); A61B 5/055 (2006.01)
CPC (source: EP US)
A61B 5/055 (2013.01 - EP US); G01R 33/4806 (2013.01 - EP US); G01R 33/50 (2013.01 - US); A61B 5/4064 (2013.01 - EP); G01R 33/56554 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 4152032 A1 20230322; CN 116583221 A 20230811; CN 116583221 B 20241018; EP 4237868 A1 20230906; EP 4237868 B1 20240221; JP 2024535813 A 20241002; US 2024272257 A1 20240815; WO 2023041339 A1 20230323
DOCDB simple family (application)
EP 21197367 A 20210917; CN 202280007916 A 20220901; EP 2022074297 W 20220901; EP 22769308 A 20220901; JP 2024516394 A 20220901; US 202218692096 A 20220901