EP 4240424 A1 20230913 - COMPOSITION COMPRISING A COMBINATION OF IMMUNE CHECKPOINT INHIBITOR AND ANTIBODY-AMATOXIN CONJUGATE FOR USE IN CANCER THERAPY
Title (en)
COMPOSITION COMPRISING A COMBINATION OF IMMUNE CHECKPOINT INHIBITOR AND ANTIBODY-AMATOXIN CONJUGATE FOR USE IN CANCER THERAPY
Title (de)
ZUSAMMENSETZUNG MIT EINER KOMBINATION AUS EINEM IMMUNCHECKPOINT-INHIBITOR UND EINEM ANTIKÖRPER-AMATOXIN-KONJUGAT ZUR VERWENDUNG IN DER KREBSTHERAPIE
Title (fr)
COMPOSITION COMPRENANT UNE COMBINAISON D'UN INHIBITEUR DE POINT DE CONTRÔLE IMMUNITAIRE ET D'UN CONJUGUÉ ANTICORPS-AMATOXINE POUR UNE UTILISATION DANS LE TRAITEMENT DU CANCER
Publication
Application
Priority
- EP 20205794 A 20201104
- EP 2021080688 W 20211104
Abstract (en)
[origin: WO2022096604A1] The present application relates to a composition comprising (a) at least one immune checkpoint inhibitor and (b) at least one conjugate, wherein said conjugate is comprising (i) a target binding moiety, (ii) at least one amatoxin, and (iii) optionally at least one linker connecting said target binding moiety with said at least one amatoxin. The present application further relates to said composition for use in treating a patient having a cancer, and to a pharmaceutical formulation comprising said composition and additional excipients, as well as to methods of producing and using said composition.
IPC 8 full level
A61K 47/68 (2017.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01)
CPC (source: EP IL KR)
A61K 39/3955 (2013.01 - EP IL KR); A61K 45/06 (2013.01 - KR); A61K 47/6831 (2017.07 - EP IL KR); A61K 47/6855 (2017.07 - EP IL KR); A61K 47/6867 (2017.07 - EP IL KR); A61P 35/00 (2017.12 - EP IL KR); C07K 16/2803 (2013.01 - EP IL KR); C07K 16/2827 (2013.01 - EP IL KR); A61K 2039/505 (2013.01 - KR); A61K 2300/00 (2013.01 - IL KR); C07K 2317/21 (2013.01 - EP IL KR); C07K 2317/76 (2013.01 - EP IL KR)
C-Set (source: EP)
Citation (search report)
See references of WO 2022096604A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2022096604 A1 20220512; AU 2021373298 A1 20230608; CA 3195572 A1 20220512; CL 2023001266 A1 20231215; CN 116744969 A 20230912; EP 4240424 A1 20230913; IL 302034 A 20230601; JP 2023548522 A 20231117; KR 20230104653 A 20230710; MX 2023005192 A 20230515
DOCDB simple family (application)
EP 2021080688 W 20211104; AU 2021373298 A 20211104; CA 3195572 A 20211104; CL 2023001266 A 20230502; CN 202180088954 A 20211104; EP 21802741 A 20211104; IL 30203423 A 20230410; JP 2023526858 A 20211104; KR 20237018353 A 20211104; MX 2023005192 A 20211104