EP 4262975 A1 20231025 - HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS
Title (en)
HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS
Title (de)
HETEROCYCLISCHE DERIVATE ALS P2X7-REZEPTORANTAGONISTEN
Title (fr)
DÉRIVÉS HÉTÉROCYCLIQUESEN TANT QU'ANTAGONISTES DU RÉCEPTEUR P2X7
Publication
Application
Priority
- EP 20215585 A 20201218
- EP 2021086250 W 20211216
Abstract (en)
[origin: EP4015039A1] The present invention relates to novel 1,4-substituted piperidine compounds of formula (I) having P2X7 receptor (P2X7) antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans
IPC 8 full level
A61P 1/00 (2006.01); A61K 31/4545 (2006.01); A61K 31/506 (2006.01); A61P 9/00 (2006.01); A61P 13/00 (2006.01); A61P 25/00 (2006.01); A61P 25/04 (2006.01); A61P 25/28 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 37/08 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01)
CPC (source: EP IL US)
A61P 1/00 (2017.12 - EP IL); A61P 9/00 (2017.12 - EP IL); A61P 13/00 (2017.12 - EP IL); A61P 25/00 (2017.12 - EP IL); A61P 25/04 (2017.12 - EP IL); A61P 25/28 (2017.12 - EP IL); A61P 27/02 (2017.12 - EP IL); A61P 29/00 (2017.12 - EP IL); A61P 37/08 (2017.12 - EP IL); C07D 417/14 (2013.01 - EP IL US); C07D 471/04 (2013.01 - EP IL US); C07D 487/04 (2013.01 - EP IL US); C07D 498/04 (2013.01 - EP IL US)
Citation (search report)
See references of WO 2022129365A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
EP 4015039 A1 20220622; CA 3202165 A1 20220623; CN 117157291 A 20231201; EP 4262975 A1 20231025; IL 303563 A 20230801; JP 2023554021 A 20231226; US 2024034737 A1 20240201; WO 2022129365 A1 20220623
DOCDB simple family (application)
EP 20215585 A 20201218; CA 3202165 A 20211216; CN 202180090855 A 20211216; EP 2021086250 W 20211216; EP 21836564 A 20211216; IL 30356323 A 20230608; JP 2023535964 A 20211216; US 202118265023 A 20211216