EP 4267108 A1 20231101 - SELF-REPLICATING RNA AND USES THEREOF
Title (en)
SELF-REPLICATING RNA AND USES THEREOF
Title (de)
SELBSTREPLIZIERENDE RNA UND VERWENDUNGEN DAVON
Title (fr)
ARN AUTORÉPLIQUANT ET UTILISATIONS ASSOCIÉES
Publication
Application
Priority
IB 2022051021 W 20220207
Abstract (en)
[origin: WO2023148527A1] The present disclosure relates to self-replicating RNA encoding an antigen from severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) and uses thereof. Specifically, the disclosure provides a self-replicating RNA or a monocistronic self-replicating RNA comprising a nucleotide sequence encoding an antigen operably linked to a'subgenomic promoter, wherein the antigen is from SARS-CoV-2, and is a spike (S) protein or a nucleocapsid (N) protein.
IPC 8 full level
A61K 9/127 (2006.01); A61K 39/12 (2006.01); A61K 39/215 (2006.01); A61K 48/00 (2006.01); C07H 21/04 (2006.01); C12N 15/00 (2006.01); C12N 15/113 (2010.01)
CPC (source: EP)
A61K 9/127 (2013.01); C07K 14/005 (2013.01); C12N 15/86 (2013.01); C12N 2770/20022 (2013.01); C12N 2770/20034 (2013.01); C12N 2770/36143 (2013.01)
Citation (search report)
See references of WO 2023148527A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2023148527 A1 20230810; BR 112023015660 A2 20231024; CA 3207885 A1 20230807; CN 116916891 A 20231020; EP 4267108 A1 20231101; IL 304699 A 20230901
DOCDB simple family (application)
IB 2022051021 W 20220207; BR 112023015660 A 20220207; CA 3207885 A 20220207; CN 202280011346 A 20220207; EP 22920982 A 20220207; IL 30469923 A 20230724