EP 4308106 A1 20240124 - MICROSPHERE FORMULATIONS COMPRISING NALTREXONE AND METHODS FOR MAKING AND USING THE SAME
Title (en)
MICROSPHERE FORMULATIONS COMPRISING NALTREXONE AND METHODS FOR MAKING AND USING THE SAME
Title (de)
MIKROKUGELFORMULIERUNGEN MIT NALTREXON UND VERFAHREN ZUR HERSTELLUNG UND VERWENDUNG DAVON
Title (fr)
FORMULATIONS DE MICROSPHÈRES COMPRENANT DE LA NALTREXONE ET LEURS MÉTHODES DE PRÉPARATION ET D'UTILISATION
Publication
Application
Priority
- US 202163161159 P 20210315
- US 202163161187 P 20210315
- US 202263266660 P 20220111
- US 2022070941 W 20220303
Abstract (en)
[origin: WO2022198167A1] Microsphere formulations comprising naltrexone are provided. The microsphere formulations comprise polymer microspheres, each polymer microsphere comprising: (i) naltrexone; and (ii) a biodegradable polymer comprising a POE or a PLA, wherein each polymer microsphere comprises a drug load of naltrexone of at least 40% by weight of the polymer microsphere, and wherein the polymer microspheres have an average particle size of about 25 mm to about 55 mm (D50). Methods for making and using the microsphere formulations are also provided.
IPC 8 full level
A61K 31/337 (2006.01); A61K 31/485 (2006.01); A61K 31/513 (2006.01)
CPC (source: EP)
A61K 9/0019 (2013.01); A61K 9/06 (2013.01); A61K 9/10 (2013.01); A61K 9/1647 (2013.01); A61K 31/485 (2013.01); A61K 47/38 (2013.01); A61K 9/19 (2013.01)
Citation (search report)
See references of WO 2022198167A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
DOCDB simple family (application)
US 2022070941 W 20220303; EP 22772358 A 20220303