EP 4308680 A1 20240124 - CELL CULTURE CHAMBER AND METHOD FOR CULTIVATING CELLS AND FOR IN VITRO PRODUCTION OF CELL LAYERS AND ORGAN MODELS
Title (en)
CELL CULTURE CHAMBER AND METHOD FOR CULTIVATING CELLS AND FOR IN VITRO PRODUCTION OF CELL LAYERS AND ORGAN MODELS
Title (de)
ZELLKULTURKAMMER UND VERFAHREN ZUR KULTIVIERUNG VON ZELLEN UND ZUR IN VITRO HERSTELLUNG VON ZELLSCHICHTEN UND ORGANMODELLEN
Title (fr)
CHAMBRE DE CULTURE CELLULAIRE ET PROCÉDÉ DE MISE EN CULTURE DE CELLULES ET DE PRODUCTION IN VITRO DE COUCHES CELLULAIRES ET DE MODÈLES D'ORGANES
Publication
Application
Priority
- DE 102021106915 A 20210319
- EP 2022057258 W 20220318
Abstract (en)
[origin: WO2022195124A1] The invention relates to a cell culture chamber (1) for in-vitro production and cultivation of cell layers and organ models, having two permeable first and second channels (3, 4) which are arranged one above the other and are separated from one another by a porous membrane (8) having two lateral faces, one cell substrate (9, 10) each being formed by the lateral faces of the membrane (8). The cell culture chamber (1) is characterised in that at least the inner walls of the first and the second channels (3, 4) consist of polybutylene terephthalate (PBT). The invention further relates to a method for cultivating human or animal cells, in particular liver sinusoidal endothelial cells, alone and in co-culture with hepatocytes and immune cells.
IPC 8 full level
CPC (source: EP US)
C12M 21/08 (2013.01 - US); C12M 25/02 (2013.01 - EP); C12M 25/04 (2013.01 - US); C12M 29/06 (2013.01 - US); C12M 35/08 (2013.01 - EP US); C12N 5/0697 (2013.01 - US); C12N 2502/00 (2013.01 - US); C12N 2513/00 (2013.01 - US); C12N 2533/52 (2013.01 - US); C12N 2533/54 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
DE 102021106915 A1 20220922; CA 3212075 A1 20220922; EP 4308680 A1 20240124; JP 2024511944 A 20240318; US 2024010993 A1 20240111; WO 2022195124 A1 20220922
DOCDB simple family (application)
DE 102021106915 A 20210319; CA 3212075 A 20220318; EP 2022057258 W 20220318; EP 22716912 A 20220318; JP 2023555400 A 20220318; US 202318469397 A 20230918