Global Patent Index - EP 4314012 A1

EP 4314012 A1 20240207 - IMMUNOMODULATORS

Title (en)

IMMUNOMODULATORS

Title (de)

IMMUNMODULATOREN

Title (fr)

IMMUNOMODULATEURS

Publication

EP 4314012 A1 20240207 (EN)

Application

EP 22721158 A 20220324

Priority

  • US 202163165455 P 20210324
  • US 2022021760 W 20220324

Abstract (en)

[origin: WO2022204412A1] The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

IPC 8 full level

C07K 7/08 (2006.01); A61K 38/10 (2006.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01)

CPC (source: EP KR US)

A61K 47/54 (2017.08 - EP KR); A61K 47/542 (2017.08 - EP KR US); A61K 47/548 (2017.08 - EP KR US); A61P 31/00 (2018.01 - KR); A61P 35/00 (2018.01 - EP KR); A61P 37/04 (2018.01 - KR); C07K 7/08 (2013.01 - EP); C07K 7/54 (2013.01 - KR US); A61K 38/00 (2013.01 - KR US)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

Designated validation state (EPC)

KH MA MD TN

DOCDB simple family (publication)

WO 2022204412 A1 20220929; CN 117157306 A 20231201; EP 4314012 A1 20240207; JP 2024512074 A 20240318; KR 20230160321 A 20231123; US 2024199701 A1 20240620

DOCDB simple family (application)

US 2022021760 W 20220324; CN 202280023007 A 20220324; EP 22721158 A 20220324; JP 2023558898 A 20220324; KR 20237035909 A 20220324; US 202218551319 A 20220324