EP 4320094 A1 20240214 - NOVEL MODULATORS OF THE MELATONIN RECEPTORS AS WELL AS METHOD OF MANUFACTURE AND USES THEREOF
Title (en)
NOVEL MODULATORS OF THE MELATONIN RECEPTORS AS WELL AS METHOD OF MANUFACTURE AND USES THEREOF
Title (de)
NEUE MODULATOREN DER MELATONINREZEPTOREN SOWIE VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG
Title (fr)
NOUVEAUX MODULATEURS DES RÉCEPTEURS DE LA MÉLATONINE, LEUR PROCÉDÉ DE PRODUCTION ET LEURS UTILISATIONS
Publication
Application
Priority
- US 202163200980 P 20210407
- CA 2022050525 W 20220406
Abstract (en)
[origin: WO2022213195A1] There is provided compounds of formula (I) or a pharmaceutically acceptable salt thereof, which are melatonin MT2 agonists, as well as pharmaceutical compositions comprising such compounds. The invention also provides the use of the compounds and pharmaceutically acceptable salts thereof described herein (or pharmaceutical compositions comprising same) for managing or treating a disease, disorder or condition associated with melatonin receptor activity such as pain, neuropsychiatric disorders, sleep, chronobiological and circadian rhythm disorders, hyperthermia, and metabolic disorders. (I).
IPC 8 full level
C07C 233/36 (2006.01); A61K 31/222 (2006.01); A61K 31/265 (2006.01); A61K 31/27 (2006.01); A61K 31/40 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01); C07C 271/64 (2006.01); C07D 207/16 (2006.01)
CPC (source: EP)
A61P 25/00 (2018.01); A61P 29/00 (2018.01); C07C 231/12 (2013.01); C07C 271/64 (2013.01); C07D 207/16 (2013.01)
C-Set (source: EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2022213195 A1 20221013; CA 3214318 A1 20221013; EP 4320094 A1 20240214; JP 2024516114 A 20240412
DOCDB simple family (application)
CA 2022050525 W 20220406; CA 3214318 A 20220406; EP 22783731 A 20220406; JP 2023562247 A 20220406