EP 4347782 A1 20240410 - METHODS TO PRODUCE DEFINED, SPHERICAL, BIO-DEGRADABLE MACROPOROUS MICROCARRIERS/HYDROGELS FOR CELLULAR AGRICULTURE
Title (en)
METHODS TO PRODUCE DEFINED, SPHERICAL, BIO-DEGRADABLE MACROPOROUS MICROCARRIERS/HYDROGELS FOR CELLULAR AGRICULTURE
Title (de)
VERFAHREN ZUR HERSTELLUNG DEFINIERTER, KUGELFÖRMIGER, BIOLOGISCH ABBAUBARER MAKROPORÖSER MIKROTRÄGER/HYDROGELE FÜR DIE ZELLULÄRE LANDWIRTSCHAFT
Title (fr)
PROCÉDÉS DE PRODUCTION DE MICROSUPPORTS/HYDROGELS MACROPOREUX, SPHÉRIQUES ET BIODÉGRADABLES POUR L'AGRICULTURE CELLULAIRE
Publication
Application
Priority
- US 202163192700 P 20210525
- US 202163290659 P 20211217
- US 202217751943 A 20220524
- IB 2022054873 W 20220525
Abstract (en)
[origin: WO2022249076A1] Biocompatible macroporous microcarriers, including microcarrier beads, microspheres, capsules, microsponges, hydrogels and other matrix forms, appropriate for use in a shaking flask or bioreactor to culture cells are described herein that can be used to create an edible structure for consumption or research investigation. Biocompatible, macroporous microcarriers can be dissolved or remain in the final product. Biocompatible macroporous microcarriers are formed by saccharides that are cross-linked via chemical induction with agitated cryo-gelation. Cross-linked macroporous, saccharide-microcarriers are coupled to adherence factors that enable cell binding. Finally, the cells are attached to the microcarrier for proliferation.
IPC 8 full level
C12M 1/12 (2006.01); C12N 5/00 (2006.01); C12N 5/077 (2010.01)
CPC (source: EP)
C12M 25/14 (2013.01); C12M 25/16 (2013.01); C12N 5/0658 (2013.01); A23L 13/00 (2016.08); C12N 2513/00 (2013.01); C12N 2533/70 (2013.01); C12N 2535/00 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
DOCDB simple family (application)
IB 2022054873 W 20220525; EP 22729799 A 20220525