EP 4351650 A1 20240417 - COMPOSITION AND METHOD FOR DUAL TARGETING IN TREATMENT OF NEUROENDOCRINE TUMORS
Title (en)
COMPOSITION AND METHOD FOR DUAL TARGETING IN TREATMENT OF NEUROENDOCRINE TUMORS
Title (de)
ZUSAMMENSETZUNG UND VERFAHREN FÜR DUALES TARGETING BEI DER BEHANDLUNG VON NEUROENDOKRINEN TUMOREN
Title (fr)
COMPOSITION ET MÉTHODE DE DOUBLE CIBLAGE DANS LE TRAITEMENT DE TUMEURS NEUROENDOCRINES
Publication
Application
Priority
- US 202117340843 A 20210607
- US 2022031876 W 20220602
Abstract (en)
[origin: WO2022260918A1] Chemical compositions and methods of synthesis thereof. The compositions disclosed and described herein are directed toward thyroid hormone ανβ3 integrin receptor antagonists conjugated to targets of the norepinephrine transporter (NET) or the catecholamine transporter. The compositions have a dual targeting effect and increased targeting efficiency in the treatment and diagnostic imaging of neuroendocrine tumors.
IPC 8 full level
A61K 47/22 (2006.01); A61K 31/22 (2006.01); A61K 47/60 (2017.01); A61P 35/00 (2006.01)
CPC (source: EP)
A61K 47/55 (2017.07); A61K 49/0032 (2013.01); A61K 49/0052 (2013.01); A61P 35/00 (2017.12)
Citation (search report)
See references of WO 2022260918A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2022260918 A1 20221215; AU 2022287943 A1 20231207; CA 3220332 A1 20221215; CN 117412772 A 20240116; EP 4351650 A1 20240417; JP 2024520888 A 20240524
DOCDB simple family (application)
US 2022031876 W 20220602; AU 2022287943 A 20220602; CA 3220332 A 20220602; CN 202280039629 A 20220602; EP 22820793 A 20220602; JP 2024519490 A 20220602