EP 4384160 A1 20240619 - HETEROCYCLIC COMPOUNDS AND METHODS OF USE
Title (en)
HETEROCYCLIC COMPOUNDS AND METHODS OF USE
Title (de)
HETEROCYCLISCHE VERBINDUNGEN UND VERFAHREN ZUR VERWENDUNG
Title (fr)
COMPOSÉS HÉTÉROCYCLIQUES ET PROCÉDÉS D'UTILISATION
Publication
Application
Priority
- US 202163231543 P 20210810
- US 202163289579 P 20211214
- US 2022039971 W 20220810
Abstract (en)
[origin: WO2023018812A1] The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula (I) : wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
IPC 8 full level
A61K 31/33 (2006.01); A61K 31/395 (2006.01); A61K 31/519 (2006.01)
CPC (source: EP)
A61K 45/06 (2013.01); C07D 519/00 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2023018812 A1 20230216; AU 2022325771 A1 20240215; CA 3228310 A1 20230216; EP 4384160 A1 20240619; JP 2024532734 A 20240910; MX 2024001893 A 20240229; TW 202330529 A 20230801
DOCDB simple family (application)
US 2022039971 W 20220810; AU 2022325771 A 20220810; CA 3228310 A 20220810; EP 22856568 A 20220810; JP 2024507879 A 20220810; MX 2024001893 A 20220810; TW 111130111 A 20220810