EP 4387734 A1 20240626 - METHOD FOR PREVENTING ENTRY AND REPLICATION OF ENVELOPED VIRUSES
Title (en)
METHOD FOR PREVENTING ENTRY AND REPLICATION OF ENVELOPED VIRUSES
Title (de)
VERFAHREN ZUR VERHINDERUNG DES EINTRITTS UND DER REPLIKATION VON EINGEHÜLLTEN VIREN
Title (fr)
PROCÉDÉ DESTINÉ À EMPÊCHER L'ENTRÉE ET LA RÉPLICATION DE VIRUS ENVELOPPÉS
Publication
Application
Priority
- US 202163235772 P 20210822
- US 202117472604 A 20210911
- US 202163294067 P 20211227
- US 202263308782 P 20220210
- US 202263396040 P 20220808
- US 2022040749 W 20220818
Abstract (en)
[origin: WO2023027939A1] The invention provides the use of a formulation containing cyclodextrin, quercetin and zinc at appropriate concentrations to mitigate infections by enveloped viruses. While the different forms of cyclodextrin prevent the entry of coated viruses into host cells by extracting and sequestering cholesterol molecules at the virus envelope and at the host cell plasma membrane, the ionophore quercetin enables cellular entry of zinc, thereby inhibiting viral replication by altering polymerase activity in the host cell.
IPC 8 full level
A61P 31/14 (2006.01); A61K 31/12 (2006.01); A61K 31/352 (2006.01); A61K 33/30 (2006.01)
CPC (source: EP)
A61K 9/0078 (2013.01); A61K 31/352 (2013.01); A61K 31/724 (2013.01); A61K 33/30 (2013.01); A61P 31/14 (2018.01)
C-Set (source: EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2023027939 A1 20230302; EP 4387734 A1 20240626; EP 4393497 A2 20240703; EP 4393497 A3 20240821
DOCDB simple family (application)
US 2022040749 W 20220818; EP 22861909 A 20220818; EP 24167332 A 20220818