(19)
(11)EP 3 039 129 A1

(12)

(43)Date of publication:
06.07.2016 Bulletin 2016/27

(21)Application number: 14761780.7

(22)Date of filing:  28.08.2014
(51)International Patent Classification (IPC): 
C12N 7/02(2006.01)
C12N 15/864(2006.01)
(86)International application number:
PCT/US2014/053281
(87)International publication number:
WO 2015/031686 (05.03.2015 Gazette  2015/09)
(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30)Priority: 30.08.2013 US 201361872523 P

(71)Applicant: Amgen Inc.
Thousand Oaks, California 91320-1799 (US)

(72)Inventors:
  • LEE, Grace Ki Jeong
    Simi Valley California 93065 (US)
  • PLEWA, Cherylene
    Simi Valley California 93063 (US)
  • SHENG, Jackie Z.
    Thousand Oaks California 91362 (US)
  • WOLFE, Thomas Gerard
    Simi Valley California 93065 (US)
  • ZHAO, Huiren
    Thousand Oaks California 91362 (US)

(74)Representative: Grünecker Patent- und Rechtsanwälte PartG mbB 
Leopoldstraße 4
80802 München
80802 München (DE)

  


(54)HIGH TITER RECOMBINANT AAV VECTOR PRODUCTION IN ADHERENT AND SUSPENSION CELLS