(19)
(11)EP 2 705 032 A1

(12)

(43)Date of publication:
12.03.2014 Bulletin 2014/11

(21)Application number: 12718651.8

(22)Date of filing:  02.05.2012
(51)International Patent Classification (IPC): 
C07D 401/10(2006.01)
A61P 35/00(2006.01)
A61K 31/4709(2006.01)
(86)International application number:
PCT/EP2012/057978
(87)International publication number:
WO 2012/150234 (08.11.2012 Gazette  2012/45)
(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30)Priority: 04.05.2011 GB 201107325

(71)Applicant: Glaxosmithkline LLC
Philadelphia, PA 19102 (US)

(72)Inventors:
  • AMANS, Dominique
    Stevenage Hertfordshire SG1 2NY (GB)
  • DEMONT, Emmanuel, Hubert
    Stevenage Hertfordshire SG1 2NY (GB)
  • JONES, Katherine, Louise
    Stevenage Hertfordshire SG1 2NY (GB)
  • SEAL, Jonathan, Thomas
    Stevenage Hertfordshire SG1 2NY (GB)
  • WALKER, Ann, Louise
    Stevenage Hertfordshire SG1 2NY (GB)

(74)Representative: Shore, Andrew David 
GlaxoSmithKline Corporate Intellectual Property (CN 925.1) 980 Great West Road
Brentford, Middlesex TW8 9GS
Brentford, Middlesex TW8 9GS (GB)

  


(54)DIHYDROQUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS