(19)
(11)EP 2 958 592 A1

(12)

(43)Date of publication:
30.12.2015 Bulletin 2015/53

(21)Application number: 14706535.3

(22)Date of filing:  21.02.2014
(51)International Patent Classification (IPC): 
A61K 45/06(2006.01)
(86)International application number:
PCT/EP2014/053377
(87)International publication number:
WO 2014/128235 (28.08.2014 Gazette  2014/35)
(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME

(30)Priority: 22.02.2013 US 201361768253 P
12.06.2013 US 201361834317 P

(71)Applicant: F.Hoffmann-La Roche AG
4070 Basel (CH)

(72)Inventors:
  • RAHA, Debasish
    South San Francisco, California 94080 (US)
  • SETTLEMAN, Jeffrey
    South San Francisco, California 94080 (US)
  • WILSON, Timothy R.
    South San Francisco, California 94080 (US)

(74)Representative: Beyermann, Jochen Carl 
F. Hoffmann-La Roche AG CLP - Patent Department Grenzacherstrasse 124
4070 Basel
4070 Basel (CH)

  


(54)METHODS OF TREATING CANCER AND PREVENTING DRUG RESISTANCE