(19) | |
| (11) | EP 0 267 723 A3 |
(12) | EUROPEAN PATENT APPLICATION |
(88) | Date of publication A3: | | 06.12.1989 Bulletin 1989/49 |
(43) | Date of publication A2: | | 18.05.1988 Bulletin 1988/20 |
(22) | Date of filing: 02.11.1987 |
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(84) | Designated Contracting States: | | AT BE CH DE ES FR GB GR IT LI LU NL SE |
(30) | Priority: | 12.11.1986 US 930193
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(71) | Applicant: Merck & Co., Inc. | | Rahway
New Jersey 07065-0900 (US) |
| (72) | Inventors: | | - Doherty, James B.
New Milford
New Jersey 07646 (US) - Finke, Paul E.
Milltown
New Jersey 08850 (US) - Firestone, Raymond A.
Westfield
New Jersey 07090 (US) - Hagmann, William K.
Westfield
New Jersey 07090 (US) - Thompson, Kevan R.
Westfield
New Jersey 07090 (US) - Shah, Shrenik K.
Metuchen
New Jersey 08840 (US)
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(74) | Representative: Cole, William Gwyn | | European Patent Department
Merck & Co., Inc.
Terlings Park
Eastwick Road Harlow
Essex CM20 2QR Harlow
Essex CM20 2QR (GB) |
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(54) | New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents |
(57) New substituted cephalosporin sulfones are found to be potent elastase inhibitors and thereby useful anti-inflammatory/antidegenerative agents.