(19) | |
| (11) | EP 0 264 914 A3 |
(12) | EUROPEAN PATENT APPLICATION |
(88) | Date of publication A3: | | 14.06.1989 Bulletin 1989/24 |
(43) | Date of publication A2: | | 27.04.1988 Bulletin 1988/17 |
(22) | Date of filing: 20.10.1987 |
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(84) | Designated Contracting States: | | DE FR GB |
(30) | Priority: | 21.10.1986 JP 250013/86
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(71) | Applicant: KYOWA HAKKO KOGYO CO., LTD. | | Chiyoda-ku,
Tokyo (JP) |
| (72) | Inventors: | | - Katsumata, Ryoichi
Machida-shi
Tokyo (JP) - Ozaki, Akio
Hofu-shi
Yamaguchi-ken (JP) - Ikeda, Masato
Sagamihara-shi
Kanagawa-ken (JP)
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(74) | Representative: VOSSIUS & PARTNER | | Postfach 86 07 67 81634 München 81634 München (DE) |
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(54) | Process for producing L-phenylalanine |
(57) The invention relates to a bacterial process for producing L-phenylalanine. The process utilizes a
Corynebacterium or
Brevibacterium host which is transformed with a recombinant DNA. The recombinant DNA harbors a DNA containing a gene which encodes 3-deoxy-D-arabino-hepturosonate-7-phosphate synthase, chorismate mutase and prephenate dehydratase. The transformant is then cultured in order to accumulate L-phenylalanine in the culture medium and the L-phenylalanine is recovered therefrom.