(19) | |
| (11) | EP 0 580 268 A3 |
(12) | EUROPEAN PATENT APPLICATION |
(88) | Date of publication A3: | | 23.02.1994 Bulletin 1994/08 |
(43) | Date of publication A2: | | 26.01.1994 Bulletin 1994/04 |
(22) | Date of filing: 29.09.1989 |
| (51) | International Patent Classification (IPC)5: A61K 31/557 |
|
(84) | Designated Contracting States: | | AT BE CH DE ES FR GB GR IT LI LU NL SE |
(30) | Priority: | 01.10.1988 JP 248720/88 01.10.1988 JP 248721/88
|
(62) | Application number of the earlier application in accordance with Art. 76 EPC: | | 89310016.4 / 0366279 |
(71) | Applicant: R-TECH UENO, LTD. | | Osaka-shi,
Osaka-fu (JP) |
| (72) | Inventors: | | - Ueno, Ryuzo
Nishinomiya-shi,
Hyogo-ken (JP) - Ueno, Ryuji
Nishinomiya-shi,
Hyogo-ken (JP) - Oda, Tomio
Sanda-shi,
Hyogo-ken (JP)
|
(74) | Representative: Atkinson, Peter Birch et al | | MARKS & CLERK,
Sussex House,
83-85 Mosley Street Manchester M2 3LG Manchester M2 3LG (GB) |
|
| | | | Remarks: | | This application was filed on 17 - 09 - 1993 as a divisional application to the application mentioned under INID code 60. | |
(54) | Ocular hypotensive agents |
(57) The present invention relates to an ocular hypotensive composition and a composition for treatment of glaucoma which comprises an amount of 20-substituted 15-keto-PGs effective as an ocular hypotensive agent; these compounds exhibit no or little side effect such as transient ocular hypertensive response, hyperemia of conjunctiva or of iris, dacryops, lema, closed eye and the like.