(19)
(11)EP 2 769 220 B8

(12)CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15)Correction information:
Corrected version no 1 (W1 B1)

(48)Corrigendum issued on:
18.11.2020 Bulletin 2020/47

(45)Mention of the grant of the patent:
15.07.2020 Bulletin 2020/29

(21)Application number: 12772445.8

(22)Date of filing:  14.08.2012
(51)International Patent Classification (IPC): 
G01N 33/564(2006.01)
C07K 14/47(2006.01)
C07K 16/28(2006.01)
A61K 38/17(2006.01)
G01N 33/538(2006.01)
(86)International application number:
PCT/IB2012/054142
(87)International publication number:
WO 2013/057599 (25.04.2013 Gazette  2013/17)

(54)

Biomarker for autoimmune disease

Biomarker für autoimmunologische Krankheit

Biomerqueur pour la maladie autoimmunologique


(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30)Priority: 17.10.2011 GR 20110100593

(43)Date of publication of application:
27.08.2014 Bulletin 2014/35

(73)Proprietor: Tzartos, Socrates
116 21 Kaisariani (GR)

(72)Inventors:
  • TZARTOS, Ioannis
    116 21 Kaisariani (GR)
  • STERGIOU, Christos
    131 23 Ilion (GR)
  • KILINDIREAS, Konstantinos
    174 55 Kalamiki (GR)
  • TZARTOS, Socrates
    11621 Kaisariani (GR)

(74)Representative: D Young & Co LLP 
120 Holborn
London EC1N 2DY
London EC1N 2DY (GB)


(56)References cited: : 
US-A- 5 741 671
  
  • Nikolov, NP ET AL.: "Autoantibodies against aquaporins in primary Sjögren's Syndrome (pSS)", , 1 January 2008 (2008-01-01), XP002679357, Retrieved from the Internet: URL:https://acr.confex.com/acr/2008/webpro gram/Paper3359.html [retrieved on 2012-07-05]
  • SMITH B L ET AL: "Human red cell aquaporin CHIP. I. Molecular characterization of ABH and Colton blood group antigens.", THE JOURNAL OF CLINICAL INVESTIGATION SEP 1994 LNKD- PUBMED:7521882, vol. 94, no. 3, September 1994 (1994-09), pages 1043-1049, XP055031929, ISSN: 0021-9738
  • DENKER B M ET AL: "Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 25 OCT 1988 LNKD- PUBMED:3049610, vol. 263, no. 30, 25 October 1988 (1988-10-25), pages 15634-15642, XP002679358, ISSN: 0021-9258
  • ELEONORA FOGLIO ET AL: "Aquaporins and Neurodegenerative Diseases", CURRENT NEUROPHARMACOLOGY, vol. 8, no. 2, 1 June 2010 (2010-06-01), pages 112-121, XP055031684, ISSN: 1570-159X, DOI: 10.2174/157015910791233150
  • JOHN S. TZARTOS ET AL: "Anti-Aquaporin-1 Autoantibodies in Patients with Neuromyelitis Optica Spectrum Disorders", PLOS ONE, vol. 8, no. 9, 23 September 2013 (2013-09-23), page e74773, XP55191149, DOI: 10.1371/journal.pone.0074773
  
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).