(19)
(11)EP 2 978 860 B8

(12)CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15)Correction information:
Corrected version no 1 (W1 B1)

(48)Corrigendum issued on:
11.12.2019 Bulletin 2019/50

(45)Mention of the grant of the patent:
07.08.2019 Bulletin 2019/32

(21)Application number: 14719062.3

(22)Date of filing:  26.03.2014
(51)International Patent Classification (IPC): 
C12Q 1/6827(2018.01)
C12Q 1/6883(2018.01)
(86)International application number:
PCT/GB2014/050955
(87)International publication number:
WO 2014/155105 (02.10.2014 Gazette  2014/40)

(54)

ASSESSMENT OF RISK OF ANEUPLOIDY

BEURTEILUNG DES RISIKOS VON ANEUPLOIDIE

ÉVALUATION DU RISQUE D'ANEUPLOÏDIE


(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30)Priority: 27.03.2013 GB 201305588
10.01.2014 GB 201400397

(43)Date of publication of application:
03.02.2016 Bulletin 2016/05

(60)Divisional application:
19189461.7

(73)Proprietor: BlueGnome Ltd
Cambridge, Cambridgeshire CB21 5XE (GB)

(72)Inventor:
  • HANDYSIDE, Alan
    Brighton East Sussex BN2 9SA (GB)

(74)Representative: Murgitroyd & Company 
Scotland House 165-169 Scotland Street
Glasgow G5 8PL
Glasgow G5 8PL (GB)


(56)References cited: : 
US-A1- 2010 160 717
  
  • D. CHRISTOPIKOU ET AL: "Polar body analysis by array comparative genomic hybridization accurately predicts aneuploidies of maternal meiotic origin in cleavage stage embryos of women of advanced maternal age", HUMAN REPRODUCTION, vol. 28, no. 5, 10 March 2013 (2013-03-10) , pages 1426-1434, XP055146306, ISSN: 0268-1161, DOI: 10.1093/humrep/det053
  • ALAN H HANDYSIDE ET AL: "Multiple meiotic errors caused by predivision of chromatids in women of advanced maternal age undergoing in vitro fertilisation", EUROPEAN JOURNAL OF HUMAN GENETICS, vol. 20, no. 7, 1 July 2012 (2012-07-01), pages 742-747, XP055146383, ISSN: 1018-4813, DOI: 10.1038/ejhg.2011.272
  • ALAN H. HANDYSIDE: "Molecular origin of female meiotic aneuploidies", BIOCHIMICA ET BIOPHYSICA ACTA (BBA) - MOLECULAR BASIS OF DISEASE, vol. 1822, no. 12, 1 December 2012 (2012-12-01), pages 1913-1920, XP055146382, ISSN: 0925-4439, DOI: 10.1016/j.bbadis.2012.07.007
  • ALTARESCU G ET AL: "Gene location matters: polar body analysis has limited informativity in centromeric genes", REPRODUCTIVE BIOMEDICINE ONLINE, REPRODUCTIVE HEALTHCARE LTD, GB, vol. 18, 1 January 2009 (2009-01-01), pages S-10, XP027051939, ISSN: 1472-6483 [retrieved on 2009-01-01]
  • A. H. HANDYSIDE ET AL: "Karyomapping: a universal method for genome wide analysis of genetic disease based on mapping crossovers between parental haplotypes", JOURNAL OF MEDICAL GENETICS, vol. 47, no. 10, 25 October 2009 (2009-10-25), pages 651-658, XP055146321, ISSN: 0022-2593, DOI: 10.1136/jmg.2009.069971
  
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