(19)
(11)EP 3 313 302 B1

(12)EUROPEAN PATENT SPECIFICATION

(45)Mention of the grant of the patent:
04.12.2019 Bulletin 2019/49

(21)Application number: 16736327.4

(22)Date of filing:  22.06.2016
(51)Int. Cl.: 
A61B 17/3207  (2006.01)
(86)International application number:
PCT/US2016/038819
(87)International publication number:
WO 2016/210000 (29.12.2016 Gazette  2016/52)

(54)

TISSUE-REMOVING CATHETER WITH RECIPROCATING TISSUE-REMOVING HEAD

GEWEBEENTNAHMEKATHETER MIT HIN- UND HERBEWEGENDEM GEWEBEENTNAHMEKOPF

CATHÉTER DE RETRAIT DE TISSU MUNI DE TÊTE DE RETRAIT DE TISSU À MOUVEMENT EN VA-ET-VIENT


(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30)Priority: 25.06.2015 US 201562184278 P

(43)Date of publication of application:
02.05.2018 Bulletin 2018/18

(73)Proprietor: Covidien LP
Mansfield, MA 02048 (US)

(72)Inventors:
  • STEELE, Bradley
    Santa Rosa, CA 95403 (US)
  • MORRIS, Cassandra
    Santa Rosa, CA 95403 (US)
  • WHEALON, William
    Santa Rosa, CA 95403 (US)
  • MCPEAK, Thomas
    Santa Rosa, CA 95403 (US)

(74)Representative: Gray, James 
Withers & Rogers LLP 4 More London Riverside
London SE1 2AU
London SE1 2AU (GB)


(56)References cited: : 
US-A- 5 195 956
US-A1- 2010 125 253
US-A1- 2015 150 590
US-A1- 2009 024 085
US-A1- 2012 071 907
  
      
    Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).


    Description

    CROSS-REFERENCE TO RELATED APPLICATIONS



    [0001] The present application claims the benefit of U.S. Provisional Serial No. 62/184,278, filed June 25, 2015.

    FIELD OF THE DISCLOSURE



    [0002] The present disclosure generally relates to a tissue-removing catheter with a reciprocating tissue-removing head.

    BACKGROUND OF THE DISCLOSURE



    [0003] Diseased body lumens may include an occlusion that completely or substantially completely block flow within the lumen. For example, Chronic Total Occlusions (CTOs) are vascular lesions which totally occlude a blood vessel and thereby inhibit normal blood flow. Such occlusions can occur anywhere in a patient's vascular system, arteries, and veins, including coronary vessels, as well as carotid arteries, renal arteries, cerebral arteries, arteries of the head and neck, iliac arteries, femoral arteries, popliteal arteries, and other peripheral arteries. One method of treating CTOs includes the use of a tissue-removing device to restore the patency of the vessel. However, there are challenges in treating CTOs using current devices. US 2009/0024085 A1 discloses a tissue removing catheter having an annular shearing blade and 1 rotating tissue removing head.

    SUMMARY OF THE DISCLOSURE



    [0004] The invention is defined in claim 1. Preferred embodiments of the invention are defined in the dependent claims. A tissue-removing catheter includes a catheter body with an annular shearing blade, and a tissue-removing head that both rotates about an head axis and reciprocates along the head axis. The tissue-removing head reciprocates between a proximal position, in which the tissue-removing head is adjacent the annular shearing blade, and a distal position, in which the tissue-removing head is spaced axially from the annular shearing blade.

    [0005] Other features will be in part apparent and in part pointed out hereinafter.

    BRIEF DESCRIPTION OF THE DRAWINGS



    [0006] 

    FIG. 1 is an enlarged, partial perspective of an illustrated embodiment of a tissue-removing catheter, a tissue-removing head of the catheter being in a proximal position;

    FIG. 2 is similar to FIG. 1 with the tissue-removing head in a distal position;

    FIG. 3 is an enlarged cross section of a distal end portion of the catheter received in a body lumen adjacent a Chronic Total Occlusion (CTO), the tissue-removing head being in the proximal position;

    FIG. 4 is similar to FIG. 3, but with the tissue-removing head in the distal position and boring in the CTO;

    FIG. 5 is similar to FIG. 4, but with the tissue-removing head retracting back to the proximal position to shear tissue from the CTO;

    FIG. 6 is a perspective of the tissue-removing head and the driveshaft;

    FIG. 7 is a perspective of the tissue-removing head, the driveshaft, and a driveshaft bushing; and

    FIG. 8 is a perspective of the driveshaft bushing.



    [0007] Corresponding reference characters indicate corresponding parts throughout the drawings.

    DETAILED DESCRIPTION OF THE DISCLOSURE



    [0008] Referring to FIGS. 1 and 2 of the drawings, one embodiment of a tissue-removing catheter for removing tissue from a body lumen is generally indicated at reference numeral 10. The illustrated tissue-removing catheter 10 is particularly suitable for removing tissue (e.g., plaque) from an occlusion that has totally occluded the body lumen in order to restore the patency of the lumen. In one particular example, the catheter 10 is suitable for removing tissue from a chronic total occlusion (CTO) in a vascular lumen (e.g., an artery).

    [0009] The catheter 10 comprises a catheter body 12, a tissue-removing head, generally indicated at 14, at a distal end of the catheter body, and a rotatable driveshaft 16 operatively connected to the tissue-removing head for both rotating the tissue-removing head about head axis A and reciprocating the tissue-removing head along the head axis A. As explained in more detail below, the tissue-removing head 14 extends distally outward from the distal end of the catheter body 12 and alternates between moving in a distal direction (indicated by arrow D1) from a proximal position relative to the catheter body (FIG. 1) to a distal position (FIG. 2), and moving in a proximal direction (indicated by arrow D2) from the distal position to the proximal position (FIG. 2). The tissue-removing head 14 reciprocates in this way simultaneously with rotating about the head axis A in a cutting direction (indicated by arrow D3).

    [0010] The catheter body 12 is elongate and at least a longitudinal portion thereof is generally flexible to allow the catheter body to navigate generally tortious body lumens. The catheter body 12 is generally tubular defining an inner lumen 20 (FIGS. 3-5) extending along the catheter body in which the driveshaft 16 extends. A shearing blade 22 disposed at the distal end of the catheter body 12 shears tissue entering the inner lumen 20 during a tissue-removing operation of the catheter 10, as explained below. The illustrated shearing blade 22 has an annular shape with an inner opening partially defining the inner lumen. The catheter body 12 may comprise a torque tube including a coiled metal wire with plastic laminated over the coiled metal wire. A hypotube may be attached to a distal end of the torque tube. The hypotube may include the shearing blade 22 and may be formed from nitinol, stainless steel, carbide, cobalt chrome, MP35N, titanium, or high strength engineering plastic (e.g., radel, PEEK, delrin). The catheter body 12 may have other configurations and may be formed in other ways.

    [0011] As shown in FIGS. 1 and 2 and other drawings, the illustrated tissue-removing head 14 has a generally conical or dome-shape that tapers distally and is suitable for boring through tissue (e.g., plaque) occluding a body lumen. The tissue-removing head 14 includes a plurality of flutes 28, which in the illustrated embodiments are straight or linear as opposed to helical. The flutes 28 extend from a distal end toward a proximal end of the tissue-removing head and are spaced apart from one another around the head axis A. The flutes 28 define cutting edges that engage and remove tissue as the tissue-removing head 14 rotates and reciprocates about and along the head axis A. The tissue-removing head 14 may also have an abrasive exterior surface for abrading the tissue. For example, an abrasive material may be applied to the exterior surface of the tissue-removing head 14 or the exterior surface may otherwise be formed to be abrasive. The tissue-removing head 14 may be formed from metal or other suitable material. The tissue-removing head may be of other configurations without departing from the scope of the present invention.

    [0012] Referring to FIGS. 3-5, the driveshaft 16 is rotatable and axially movable (so as to reciprocate) within the inner lumen 20 of the body 12. A distal end of driveshaft 16 is fixedly connected to the proximal end of the tissue-removing head 14 to impart rotation and reciprocating motion to the tissue-removing head. The driveshaft 16 may be formed separately from the tissue-removing head 14 or integrally formed therewith. The driveshaft 16 may be operatively connected to the tissue-removing head 14 in other ways suitable for imparting rotation to the tissue-removing head. The distal end portion of the driveshaft 16 includes a helical thread 36 (e.g., an Archimedes' blade) surrounding the longitudinal axis of the driveshaft. The illustrated thread 36 has a variable pitch, with the pitch being relatively coarse adjacent the distal end of the thread and fine (substantially flat) adjacent the proximal end. As explained below, during the tissue-removing operation the helical thread 36 functions as a tissue-transport mechanism to transport removed tissue proximally within the inner lumen 20 of the catheter body 12. The variable pitch of the thread 36 maximizes the tissue transport speed due to the coarse pitch at a distal portion of the thread, and facilitates grinding or breaking up of tissue due to the fine pitch at a proximal portion of the thread, as explained in more detail below. In other embodiments, the driveshaft may not include the thread 36.

    [0013] Referring still to FIGS. 3-5, in the illustrated embodiment, the driveshaft 16 is connected to the catheter body 12 via a bearing or driveshaft bushing 40 attached to the catheter body in the inner lumen 20. The illustrated driveshaft bushing 40 has a generally disk-shape defining a bearing opening 42 aligned axially with the catheter body 12, and tissue openings 44 radially outward of the bearing opening and spaced apart from one another around the bearing opening. The driveshaft 16 passes through the bearing opening 42 (e.g., a central bearing opening), which is sized and shaped snugly receive the driveshaft while at the same time allowing the driveshaft to rotate and move axially (i.e., reciprocate) relative to the bushing 40 and the catheter body 12. The tissue openings 44 are sized and shaped to receive removed tissue being transported proximally within the inner lumen 20 via the thread 36, as explained in more detail below. When the tissue-removing head 14 and the driveshaft 16 are in the distal position (see e.g., FIGS. 4 and 7), the proximal portion of the thread 36 is spaced axially from a distal face of the bushing 40 to define a space therebetween in the inner lumen 20. When the tissue-removing head 14 and the driveshaft 16 are in the proximal position (see e.g., FIG. 5), the proximal portion of the thread 36 is adjacent and/or flush against the distal face of the bushing 40. As shown in FIGS. 6 and 7, the proximal end portion of the thread 36 includes grooves 48 (or ribs) or other structures which, along with the fine pitch of the thread, facilitate shearing and breaking up of removed tissue within the space between the thread and the bushing 40, as explained in more detail below. The tissue openings 44 in the bushing 40 also facilitate shearing and breaking up of removed tissue. The bushing 40 may include additional structures to facilitate shearing and breaking up of removed tissue.

    [0014] Although not illustrated, a control handle or other control device operatively connects to the proximal end of the catheter 10. The control handle includes a housing and at least one actuator in the housing for driving rotation and reciprocation of the driveshaft. In one example, the control handle may include a rotary actuator for rotating the driveshaft about the longitudinal axis and a linear actuator for reciprocating the driveshaft along the longitudinal axis. The rotary and linear actuators may share an electric motor or prime mover, or the actuators may have separate dedicated motors.

    [0015] Referring to FIG. 3, in one embodiment of a tissue-removing operation using the catheter 10, the distal end of the catheter is delivered to a target site within a body lumen BL. In one particular example, the body lumen BL is a vascular lumen (e.g., an artery) and the target site is tissue (e.g., plaque) forming a chronic total occlusion CTO. In one example, the catheter 10 may be delivered to the target site over a guidewire (not shown). The illustrated catheter 10 has a guidewire lumen 50 extending through the driveshaft and the tissue-removing head for receiving a guidewire. The catheter 10 may be delivered to the target site in other ways without departing from the scope of the present invention. At the target site, the catheter 10 can be activated using the control handle, such as by activating a control lever, button or other device to activate the at least one actuator. Upon activating the catheter, the driveshaft and the tissue-removing head both rotate about the head axis A and reciprocate along the head axis between the proximal and distal positions. Simultaneously with the activation of the catheter 10, the user may move the catheter body 12 distally toward the occlusion (as indicated by arrow D4).

    [0016] As shown in FIG. 4, the tissue-removing head bores (or reams) into the occlusion CTO as it rotates and moves distally to the distal position. As the tissue-removing head is boring, the tissue is cut by the cutting edges of the flutes 28 of the tissue-removing head 14, and simultaneously, the tissue is elastically compressed radially between the tissue-removing head and the wall of the body lumen BL, as indicated by arrows C. When the tissue-removing head 14 passes distally beyond a portion of this radially compressed tissue, the tissue rebounds radially inwardly toward the driveshaft 16 and the thread 36. Because the thread 36 is simultaneously rotating, the thread may engage the rebounded tissue and pull the tissue both toward the driveshaft 16 and proximally toward the shearing blade 22 of the catheter body 12. Moreover, from the distal position, the tissue-removing head 14 and the thread 36 move proximally (as indicated by the arrow D2) to pull the rebounded tissue proximally. During this proximal movement of the tissue-removing head 14 and the driveshaft 16 toward the proximal position, the rebounded tissue is sheared off from the occlusion as the thread and/or the tissue-removing head move proximally past the cutting blade 22 within the inner lumen 20. In the illustrated embodiment, as shown in FIG. 5, at least a proximal portion of the tissue-removing head 14 passes into the opening of the shearing blade 22 to facilitate shearing of the tissue. The sheared off or removed tissue enters the inner lumen 20 of the catheter body 12.

    [0017] Referring to FIG. 5, the removed tissue in the inner lumen 20 is transported proximally toward the bushing 40. When the driveshaft 16 is in the distal position, tissue being transported via the thread 36 enters the space in the inner lumen 20 between the proximal end portion of the thread and the distal face of the driveshaft bushing 40. As the driveshaft 16 moves proximally from the distal position (FIG. 4) to the proximal position, the proximal end portion of the thread 36 compresses the removed tissue against the distal face of the bushing 40. Rotation of the thread 36 simultaneously with the thread moving proximally to compress the removed tissue both shears the removed tissue, thereby breaking the tissue into smaller fragments, and forces the removed tissue through the tissue openings 44 of the bushing 40. In the illustrated embodiment, the removed tissue is stored in the inner lumen 20 of the catheter body 12 at a location proximal of the bushing 40.

    [0018] This operation of simultaneously rotating and reciprocating the tissue-removing head 14, while moving the catheter 10 distally, facilitates boring (or reaming) of the tissue-removing head through the occlusion CTO. In particular, the catheter 10 continues the process of the tissue-removing head 14 entering tissue, the tissue compressing then rebounding around the proximal end of the tissue-removing head, the rebounded tissue being picked up by the thread 36 and then sheared off from the occlusion CTO when the tissue-removing head and the driveshaft 16 moved proximally. Moreover, the continued rotation of the driveshaft thread 36 and the shearing and compression of the removed tissue between the proximal end of the thread and the distal face of the bushing 40 breaks up the removed tissue and moves the tissue through the bushing where it is stored in the inner lumen 20.

    [0019] Modifications and variations of the disclosed embodiments are possible without departing from the scope of the invention defined in the appended claims.

    [0020] When introducing elements of the present invention or the embodiment(s) thereof, the articles "a", "an", "the" and "said" are intended to mean that there are one or more of the elements. The terms "comprising", "including" and "having" are intended to be inclusive and mean that there may be additional elements other than the listed elements.

    [0021] As various changes could be made in the above constructions, products, and devices without departing from the scope of the invention, it is intended that all matter contained in the above description and shown in the accompanying drawings shall be interpreted as illustrative and not in a limiting sense.


    Claims

    1. A tissue-removing catheter (10) comprising:

    a catheter body (12) having opposite proximal and distal ends;

    an annular shearing blade (22) secured to the distal end of the catheter body (12); and

    a tissue-removing head (14) at the distal end of the catheter body (12), wherein the tissue-removing head (14) is configured to rotate (D3) about a head axis relative to the catheter body (12), and the tissue-removing catheter being characterized in that the tissue removing head is configured to reciprocate (D1, D2) along the head axis (A) relative to the catheter body (12) between a proximal position, in which the tissue-removing head (14) is adjacent the annular shearing blade (22), and a distal position, in which the tissue-removing head (14) is spaced axially from the annular shearing blade (22).


     
    2. The tissue-removing catheter (10) set forth in claim 1, further comprising a driveshaft (16) received in and extending along the catheter body (12), wherein the driveshaft (16) is rotatable about the catheter body (12) and operatively connected to the tissue-removing head (14) to impart rotation (D3) of the tissue-removing head (14) about the head axis (A).
     
    3. The tissue-removing catheter (10) set forth in claim 2, wherein the driveshaft (16) is reciprocatable along the catheter body (12) and operatively connected to the tissue-removing head (14) to impart reciprocation (D2) of the tissue-removing head (14) about the head axis (A).
     
    4. The tissue-removing catheter (10) set forth in claim 2, wherein the driveshaft (16) has a longitudinal axis and includes an external helical thread (36) surrounding the longitudinal axis, wherein the external helical thread (36) is configured to transport removed tissue proximally along the driveshaft (16) and within the catheter body (22) as the driveshaft (16) rotates relative to the catheter body (12).
     
    5. The tissue-removing catheter (10) set forth in claim 4, wherein the external helical thread (36) extends proximally along the longitudinal axis from adjacent the tissue-removing head (14).
     
    6. The tissue-removing catheter (10) set forth in claim 5, wherein the external helical thread (36) has a variable pitch.
     
    7. The tissue-removing catheter (10) set forth in claim 6, wherein the variable pitch of the external helical thread (36) is relatively coarse adjacent a distal end of the external helical thread (36) and relatively fine adjacent a proximal end of the external helical thread.
     
    8. The tissue-removing catheter (10) set forth in claim 4, further comprising a driveshaft bushing (40) received in the catheter body (12) and defining a bearing opening (42) extending through proximal and distal ends of the driveshaft bushing (40), wherein the driveshaft (16) extends through the bearing opening (42).
     
    9. The tissue-removing catheter (10) set forth in claim 8, wherein the driveshaft bushing (40) is fixedly attached to the catheter body (12).
     
    10. The tissue-removing catheter (10) set forth in claim 8, wherein the driveshaft bearing (40) defines a tissue opening (44) disposed radially outward from the bearing opening (42) and extending through the proximal and distal ends of the driveshaft bushing (40), wherein the tissue opening (44) is configured to allow removed tissue transported via the external helical thread (36) to pass proximally therethrough.
     
    11. The tissue-removing catheter (10) set forth in claim 10, wherein tissue opening (44) comprises a plurality of tissue openings (44) spaced apart from one another around the bearing opening (42).
     
    12. The tissue-removing catheter (10) set forth in claim 10, wherein the external helical thread (36) has a proximal end configured to abut the distal end of the driveshaft bearing (40) when the tissue-removing head (14) is in the proximal position.
     
    13. The tissue-removing catheter (10) set forth in claim 12, wherein the proximal end of the external helical thread (36) includes at least one of grooves and ribs (48) to facilitate shearing and breaking up of removed tissue between the proximal end of the external helical thread (36) and the distal end of the driveshaft bearing (40).
     
    14. The tissue-removing catheter (10) set forth in claim 1, wherein the tissue-removing head (24) and a generally conical shape that tapers distally.
     
    15. The tissue-removing catheter (10) set forth in claim 14, wherein the tissue-removing head (14) defines a plurality of flutes (18) extending from a distal end toward a proximal end of the tissue-removing head (14).
     
    16. The tissue-removing catheter (10) set forth in claim 15, wherein the flutes (28) are spaced apart from one another around the head axis (A).
     
    17. The tissue-removing catheter (10) set forth in claim 14, wherein the tissue-removing head (14) has an abrasive exterior surface.
     
    18. The tissue-removing catheter (10) set forth in claim 1, wherein the annular shearing blade (22) surrounds a proximal end portion of the tissue-removing head (14) when the tissue-removing head is in the proximal position.
     


    Ansprüche

    1. Gewebeentnahmekatheter (10), umfassend:

    einen Katheterkörper (12) mit einem gegenüberliegenden proximalen und distalen Ende;

    eine ringförmige Scherklinge (22), die an dem distalen Ende des Katheterkörpers (12) befestigt ist; und

    einen Gewebeentnahmekopf (14) an dem distalen Ende des Katheterkörpers (12), wobei der Gewebeentnahmekopf (14) so konfiguriert ist, dass er sich relativ zum Katheterkörper (12) um eine Kopfachse dreht (D3), und der Gewebeentnahmekatheter dadurch gekennzeichnet ist, dass der Gewebeentnahmekopf so konfiguriert ist, dass er sich relativ zum Katheterkörper (12) entlang der Kopfachse (A) zwischen einer proximalen Position, in der der Gewebeentnahmekopf (14) benachbart zu der ringförmigen Scherklinge (22) ist, und einer distalen Position, in der der Gewebeentnahmekopf (14) axial von der ringförmigen Scherklinge (22) beabstandet ist, hin- und herbewegt (D1, D2).


     
    2. Gewebeentnahmekatheter (10) nach Anspruch 1, ferner umfassend eine Antriebswelle (16), die in dem Katheterkörper (12) aufgenommen ist und sich entlang diesem erstreckt, wobei die Antriebswelle (16) um den Katheterkörper (12) drehbar ist und funktional mit dem Gewebeentnahmekopf (14) verbunden ist, um eine Drehung (D3) des Gewebeentnahmekopfes (14) um die Kopfachse (A) zu vermitteln.
     
    3. Gewebeentnahmekatheter (10) nach Anspruch 2, wobei die Antriebswelle (16) entlang dem Katheterkörper (12) hin- und herbewegbar ist und funktional mit dem Gewebeentnahmekopf (14) verbunden ist, um eine Hin- und Herbewegung (D2) des Gewebeentnahmekopfes (14) um die Kopfachse (A) zu vermitteln.
     
    4. Gewebeentnahmekatheter (10) nach Anspruch 2, wobei die Antriebswelle (16) eine Längsachse aufweist und ein externes Schraubengewinde (36) einschließt, das die Längsachse umgibt, wobei das externe Schraubengewinde (36) so konfiguriert ist, dass es entnommenes Gewebe proximal entlang der Antriebswelle (16) und innerhalb des Katheterkörpers (22) transportiert, wenn sich die Antriebswelle (16) relativ zum Katheterkörper (12) dreht.
     
    5. Gewebeentnahmekatheter (10) nach Anspruch 4, wobei sich das externe Schraubengewinde (36) proximal entlang der Längsachse von dem benachbarten Gewebeentnahmekopf (14) erstreckt.
     
    6. Gewebeentnahmekatheter (10) nach Anspruch 5, wobei das externe Schraubengewinde (36) eine variable Windung aufweist.
     
    7. Gewebeentnahmekatheter (10) nach Anspruch 6, wobei die variable Windung des externen Schraubengewindes (36) relativ weit benachbart zu einem distalen Ende des externen Schraubengewindes (36) ist und relativ eng benachbart zu einem proximalen Ende des externen Schraubengewindes ist.
     
    8. Gewebeentnahmekatheter (10) nach Anspruch 4, ferner umfassend eine Antriebswellenbuchse (40), die in dem Katheterkörper (12) aufgenommen ist und eine Lageröffnung (42) definiert, die sich durch ein proximales und distales Ende der Antriebswellenbuchse (40) erstreckt, wobei sich die Antriebswelle (16) durch die Lageröffnung (42) erstreckt.
     
    9. Gewebeentnahmekatheter (10) nach Anspruch 8, wobei die Antriebswellenbuchse (40) fest an dem Katheterkörper (12) angebracht ist.
     
    10. Gewebeentnahmekatheter (10) nach Anspruch 8, wobei das Antriebswellenlager (40) eine Gewebeöffnung (44) definiert, die radial außerhalb von der Lageröffnung (42) angeordnet ist und sich durch das proximale und distale Ende der Antriebswellenbuchse (40) erstreckt, wobei die Gewebeöffnung (44) so konfiguriert ist, dass entnommenes Gewebe, das über das externe Schraubengewinde (36) transportiert wird, proximal hindurchtreten kann.
     
    11. Gewebeentnahmekatheter (10) nach Anspruch 10, wobei die Gewebeöffnung (44) eine Vielzahl von Gewebeöffnungen (44) umfasst, die um die Lageröffnung (42) voneinander beabstandet sind.
     
    12. Gewebeentnahmekatheter (10) nach Anspruch 10, wobei das externe Schraubengewinde (36) ein proximales Ende aufweist, das so konfiguriert ist, dass es an dem distalen Ende des Antriebswellenlagers (40) anliegt, wenn sich der Gewebeentnahmekopf (14) in der proximalen Position befindet.
     
    13. Gewebeentnahmekatheter (10) nach Anspruch 12, wobei das proximale Ende des externen Schraubengewindes (36) mindestens eine von Nuten und Rippen (48) einschließt, um das Scheren und Brechen von entnommenem Gewebe zwischen dem proximalen Ende des externen Schraubengewindes (36) und dem distalen Ende des Antriebswellenlagers (40) zu erleichtern.
     
    14. Gewebeentnahmekatheter (10) nach Anspruch 1, wobei der Gewebeentnahmekopf (24) und eine allgemein konische Form, die sich in distaler Richtung verjüngt.
     
    15. Gewebeentnahmekatheter (10) nach Anspruch 14, wobei der Gewebeentnahmekopf (14) eine Vielzahl von Rillen (18) definiert, die sich von einem distalen Ende zu einem proximalen Ende des Gewebeentnahmekopfes (14) erstrecken.
     
    16. Gewebeentnahmekatheter (10) nach Anspruch 15, wobei die Rillen (28) um die Kopfachse (A) voneinander beabstandet sind.
     
    17. Gewebeentnahmekatheter (10) nach Anspruch 14, wobei der Gewebeentnahmekopf (14) eine abrasive äußere Oberfläche aufweist.
     
    18. Gewebeentnahmekatheter (10) nach Anspruch 1, wobei die ringförmige Scherklinge (22) einen proximalen Endabschnitt des Gewebeentnahmekopfes (14) umgibt, wenn der Gewebeentnahmekopf in der proximalen Position ist.
     


    Revendications

    1. Cathéter d'ablation de tissu (10) comprenant :

    un corps de cathéter (12) ayant des extrémités proximale et distale opposées ;

    une lame de cisaillement annulaire (22) fixée à l'extrémité distale du corps de cathéter (12) ; et

    une tête d'ablation de tissu (14) au niveau de l'extrémité distale du corps de cathéter (12), dans lequel la tête d'ablation de tissu (14) est configurée pour tourner (D3) autour d'un axe de tête par rapport au corps de cathéter (12), et le cathéter d'ablation de tissu étant caractérisé en ce que la tête d'ablation de tissu est configurée pour aller et venir (D1, D2) le long de l'axe de tête (A) par rapport au corps de cathéter (12) entre une position proximale, dans laquelle la tête d'ablation de tissu (14) est adjacente à la lame de cisaillement annulaire (22), et une position distale, dans laquelle la tête d'ablation de tissu (14) est espacée axialement de la lame de cisaillement annulaire (22).


     
    2. Cathéter d'ablation de tissu (10) selon la revendication 1, comprenant en outre une tige d'entraînement (16) reçue dans le et s'étendant le long du corps de cathéter (12), dans lequel la tige d'entraînement (16) peut tourner autour du corps de cathéter (12) et est reliée de façon opérationnelle à la tête d'ablation de tissu (14) pour communiquer une rotation (D3) de la tête d'ablation de tissu (14) autour de l'axe de tête (A).
     
    3. Cathéter d'ablation de tissu (10) selon la revendication 2, dans lequel la tige d'entraînement (16) est capable d'un mouvement de va-et-vient le long du corps de cathéter (12) et est reliée de façon opérationnelle à la tête d'ablation de tissu (14) pour communiquer un mouvement de va-et-vient (D2) de la tête d'ablation de tissu (14) autour de l'axe de tête (A).
     
    4. Cathéter d'ablation de tissu (10) selon la revendication 2, dans lequel la tige d'entraînement (16) a un axe longitudinal et inclut un filet hélicoïdal externe (36) entourant l'axe longitudinal, dans lequel le filet hélicoïdal externe (36) est configuré pour transporter un tissu retiré de façon proximale le long de la tige d'entraînement (16) et au sein du corps de cathéter (22) à mesure que la tige d'entraînement (16) tourne par rapport au corps de cathéter (12).
     
    5. Cathéter d'ablation de tissu (10) selon la revendication 4, dans lequel le filet hélicoïdal externe (36) s'étend de façon proximale le long de l'axe longitudinal à partir d'une position adjacente à la tête d'ablation de tissu (14).
     
    6. Cathéter d'ablation de tissu (10) selon la revendication 5, dans lequel le filet hélicoïdal externe (36) a un pas variable.
     
    7. Cathéter d'ablation de tissu (10) selon la revendication 6, dans lequel le pas variable du filet hélicoïdal externe (36) est relativement grossier adjacent à une extrémité distale du filet hélicoïdal externe (36) et relativement fin adjacent à une extrémité proximale du filet hélicoïdal externe.
     
    8. Cathéter d'ablation de tissu (10) selon la revendication 4, comprenant en outre une douille de tige d'entraînement (40) reçue dans le corps de cathéter (12) et définissant une ouverture de palier (42) s'étendant à travers des extrémités proximale et distale de la douille de tige d'entraînement (40), dans lequel la tige d'entraînement (16) s'étend à travers l'ouverture de palier (42).
     
    9. Cathéter d'ablation de tissu (10) selon la revendication 8, dans lequel la douille de tige d'entraînement (40) est solidarisée au corps de cathéter (12).
     
    10. Cathéter d'ablation de tissu (10) selon la revendication 8, dans lequel le palier de tige d'entraînement (40) définit une ouverture de tissu (44) disposée radialement vers l'extérieur à partir de l'ouverture de palier (42) et s'étendant à travers les extrémités proximale et distale de la douille de tige d'entraînement (40), dans lequel l'ouverture de tissu (44) est configurée pour permettre au tissu retiré transporté via le filet hélicoïdal externe (36) de passer de façon proximale à travers celui-ci.
     
    11. Cathéter d'ablation de tissu (10) selon la revendication 10, dans lequel l'ouverture de tissu (44) comprend une pluralité d'ouvertures de tissu (44) espacées les unes des autres autour de l'ouverture de palier (42).
     
    12. Cathéter d'ablation de tissu (10) selon la revendication 10, dans lequel le filet hélicoïdal externe (36) a une extrémité proximale configurée pour venir en butée contre l'extrémité distale du palier de tige d'entraînement (40) lorsque la tête d'ablation de tissu (14) est dans la position proximale.
     
    13. Cathéter d'ablation de tissu (10) selon la revendication 12, dans lequel l'extrémité proximale du filet hélicoïdal externe (36) inclut au moins l'une parmi des rainures et des nervures (48) pour faciliter un cisaillement et une rupture du tissu retiré entre l'extrémité proximale du filet hélicoïdal externe (36) et l'extrémité distale du palier de tige d'entraînement (40).
     
    14. Cathéter d'ablation de tissu (10) selon la revendication 1, dans lequel la tête d'ablation de tissu (24) et une forme généralement conique qui s'effile de façon distale.
     
    15. Cathéter d'ablation de tissu (10) selon la revendication 14, dans lequel la tête d'ablation de tissu (14) définit une pluralité de cannelures (18) s'étendant à partir d'une extrémité distale en direction d'une extrémité proximale de la tête d'ablation de tissu (14).
     
    16. Cathéter d'ablation de tissu (10) selon la revendication 15, dans lequel les cannelures (28) sont espacées les unes des autres autour de l'axe de tête (A).
     
    17. Cathéter d'ablation de tissu (10) selon la revendication 14, dans lequel la tête d'ablation de tissu (14) a une surface extérieure abrasive.
     
    18. Cathéter d'ablation de tissu (10) selon la revendication 1, dans lequel la lame de cisaillement annulaire (22) entoure une partie d'extrémité proximale de la tête d'ablation de tissu (14) lorsque la tête d'ablation de tissu est dans la position proximale.
     




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    REFERENCES CITED IN THE DESCRIPTION



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    Patent documents cited in the description