(19)
(11)EP 3 563 853 A8

(12)CORRECTED EUROPEAN PATENT APPLICATION
published in accordance with Art. 153(4) EPC

(15)Correction information:
Corrected version no 1 (W1 A1)

(48)Corrigendum issued on:
17.06.2020 Bulletin 2020/25

(43)Date of publication:
06.11.2019 Bulletin 2019/45

(21)Application number: 17888733.7

(22)Date of filing:  27.12.2017
(51)Int. Cl.: 
A61K 31/7016  (2006.01)
A61K 31/734  (2006.01)
A61P 9/00  (2006.01)
C07H 3/04  (2006.01)
C07H 1/00  (2006.01)
A61K 31/702  (2006.01)
A61P 25/28  (2006.01)
C08B 37/04  (2006.01)
C07H 3/06  (2006.01)
(86)International application number:
PCT/CN2017/118843
(87)International publication number:
WO 2018/121559 (05.07.2018 Gazette  2018/27)
(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Validation States:
MA

(30)Priority: 30.12.2016 WO PCT/CN2016/113879

(71)Applicants:
  • Shanghai Green Valley Pharmaceutical Co., Ltd.
    Pudong New Area, Shanghai 201203 (CN)
  • Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Shanghai 201203 (CN)

(72)Inventors:
  • GENG, Meiyu
    Shanghai 201203 (CN)
  • DING, Jian
    Shanghai 201203 (CN)
  • ZHANG, Zhenqing
    Suzhou Jiangsu 215123 (CN)
  • XIAO, Zhongping
    Shanghai 201200 (CN)
  • DU, Xiaoguang
    Shanghai 201203 (CN)
  • XIN, Xianliang
    Shanghai 201203 (CN)

(74)Representative: Plasseraud IP 
66, rue de la Chaussée d'Antin
75440 Paris Cedex 09
75440 Paris Cedex 09 (FR)

  


(54)COMPOSITION OF MANNURONIC DICARBOXYLIC ACID


(57) The present invention relates to a mannuronic diacid oligosaccharide composition, comprising a mannuronic diacid of Formula (III) or a pharmaceutically acceptable salt thereof, wherein n is an integer from 1 to 9, m is 0, 1 or 2, and m' is 0 or 1, and wherein the total weight of mannuronic diacids wherein n = 1-5 is 80-95% of the total weight of the composition, and the ratio of the total weight of mannuronic diacids wherein n = 1-3 to the total weight of mannuronic diacids wherein n = 4-7 is between 1.0 and 3.5.