(19)
(11)EP 3 613 734 A3

(12)EUROPEAN PATENT APPLICATION

(88)Date of publication A3:
25.03.2020 Bulletin 2020/13

(43)Date of publication A2:
26.02.2020 Bulletin 2020/09

(21)Application number: 19199941.6

(22)Date of filing:  24.02.2010
(51)International Patent Classification (IPC): 
C07D 401/12(2006.01)
(84)Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR

(30)Priority: 25.02.2009 JP 2009042975

(62)Application number of the earlier application in accordance with Art. 76 EPC:
17174350.3 / 3241826
14152159.1 / 2765130
10746231.9 / 2402313

(71)Applicant: Takeda Pharmaceutical Company Limited
Osaka-shi, Osaka 541-0045, (JP)

(72)Inventors:
  • IKEMOTO, Tomomi
    Osaka 532-8686 (JP)
  • MIZUFUNE, Hideya
    Osaka 532-8686 (JP)
  • NAGATA, Toshiaki
    Osaka 532-8686 (JP)
  • SERA, Misayo
    Osaka 532-8686 (JP)
  • FUKUDA, Naohiro
    Osaka 532-8686 (JP)
  • YAMASAKI, Takeshi
    Osaka 532-8686 (JP)

(74)Representative: Jones, Nicholas Andrew 
Withers & Rogers LLP 4 More London Riverside
London, SE1 2AU
London, SE1 2AU (GB)

  


(54)PROCESS FOR PRODUCING PYRROLE COMPOUND


(57) The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.







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