(19) | |
| (11) | EP 3 633 032 A3 |
(12) | EUROPEAN PATENT APPLICATION |
(88) | Date of publication A3: | | 29.07.2020 Bulletin 2020/31 |
(43) | Date of publication A2: | | 08.04.2020 Bulletin 2020/15 |
(22) | Date of filing: 27.08.2015 |
| (51) | International Patent Classification (IPC): |
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(84) | Designated Contracting States: | | AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
(30) | Priority: | 28.08.2014 US 201462043204 P 29.08.2014 US 201462043882 P
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(62) | Application number of the earlier application in accordance with Art. 76 EPC: | | 15836709.4 / 3186375 |
(71) | Applicant: North Carolina State University | | Raleigh, North Carolina 27606 (US) |
| (72) | Inventors: | | - BARRANGOU, Rodolphe
Raleigh, North Carolina 27695 (US) - BRINER, Alexandra E.
Cary, North Carolina 27511 (US)
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(74) | Representative: HGF | | 1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB) |
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(54) | NOVEL CAS9 PROTEINS AND GUIDING FEATURES FOR DNA TARGETING AND GENOME EDITING |
(57) The present invention is directed to methods and compositions comprising novel CRISPR polypeptides and polynucleotides for site-specific cleavage and nicking of nucleic acids, transcriptional control and genome editing.