(19)
(11)EP 3 988 985 A3

(12)EUROPEAN PATENT APPLICATION

(88)Date of publication A3:
13.07.2022 Bulletin 2022/28

(43)Date of publication A2:
27.04.2022 Bulletin 2022/17

(21)Application number: 21212720.3

(22)Date of filing:  01.02.2011
(51)International Patent Classification (IPC): 
G02B 7/08(2021.01)
G02B 21/24(2006.01)
(52)Cooperative Patent Classification (CPC):
G02B 21/244
(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(62)Application number of the earlier application in accordance with Art. 76 EPC:
11702907.4 / 2671113

(71)Applicant: Roche Diagnostics Hematology, Inc.
Indianapolis IN 46250 (US)

(72)Inventor:
  • ZAHNISER, Michael
    Jamaica Plain, 02130 (US)

(74)Representative: Peterreins Schley 
Patent- und Rechtsanwälte PartG mbB Hermann-Sack-Strasse 3
80331 München
80331 München (DE)

  


(54)FAST AUTO-FOCUS IN MICROSCOPIC IMAGING


(57) The disclosure relates to methods and systems for automatically focusing multiple images of one or more objects on a substrate. The methods include obtaining, by a processor, a representative focal distance for a first location on the substrate based on a set of focal distances at known locations on the substrate. The methods also include acquiring, by an image acquisition device, a set of at least two images of the first location. The images are each acquired using a different focal distance at an offset from the representative focal distance. The methods further include estimating, by a processor, an ideal focal distance corresponding to the first location based on comparing a quality of focus for each of the images, and storing the estimated ideal focal distance and the first location in the set of focal distances at known locations.







Search report















Search report