(19)
(11)EP 4 234 560 A3

(12)EUROPEAN PATENT APPLICATION

(88)Date of publication A3:
13.09.2023 Bulletin 2023/37

(43)Date of publication A2:
30.08.2023 Bulletin 2023/35

(21)Application number: 23160303.6

(22)Date of filing:  22.10.2019
(51)International Patent Classification (IPC): 
C07D 498/22(2006.01)
C07D 498/18(2006.01)
A61K 47/54(2017.01)
A61P 31/18(2006.01)
A61K 31/5365(2006.01)
A61K 9/14(2006.01)
(52)Cooperative Patent Classification (CPC):
C07D 498/14; A61K 31/4985; A61P 31/18; A61K 31/513; A61K 31/47; A61K 31/553; A61K 9/0019; A61K 9/146; A61K 47/542; C07D 498/22
(84)Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30)Priority: 22.10.2018 US 201862748798 P

(62)Application number of the earlier application in accordance with Art. 76 EPC:
19877349.1 / 3870174

(71)Applicant: Board of Regents of the University of Nebraska
Lincoln, NE 68583 (US)

(72)Inventors:
  • GENDELMAN, Howard E.
    Omaha, 68154 (US)
  • EDAGWA, Benson
    Omaha, 68131 (US)

(74)Representative: HGF 
HGF Limited 1 City Walk
Leeds LS11 9DX
Leeds LS11 9DX (GB)

  


(54)ANTIVIRAL PRODRUGS AND NANOFORMULATIONS THEREOF


(57) The present invention provides prodrugs and methods of use thereof.







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