Description     Claims     Drawing  

US5677437A   [0048] 
US5792844A   [0048] 
US5783682A   [0048] 
US5637684A   [0048] 
US5034506A   [0048] 
WO2005040378A   [0082] 
US11524528B   [0164] 

Non-homologous end joining as a mechanism of DNA repair   [0163] 
An antisense oligonucleotide targeted to human Ku80 messenger RNA sensitizes M059K malignant glioma cells to ionizing radiation, bleomycin, and etoposide but not DNA cross-linking agents   [0163] 
Mechanisms of enhancement of cytotoxicity in etoposide and ionising radiation-treated cells by the protein kinase inhibitor wortmannin   [0163] 
Oligonucleotide interactions. III.Conformational differences between deoxy-and ribodinucleoside phosphates   [0163] 
DNA looping by Ku and the DNA-dependent protein kinase   [0163] 
A means to a DNA end: The many roles of Ku   [0163] 
Vanillins--a novel family of DNA-PK inhibitors   [0163] 
A targeted chain-termination mutation in the mouse Ape gene results in multiple intestinal tumors   [0163] 
Sensing and repairing DNA double-strand breaks   [0163] 
Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneoustumorigenesis in mice   [0163] 
A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation   [0163] 
The tumor suppressor p53 can reduce stable transfection in the presence of irradiation   [0163] 
Modification of the ionizing radiation response in living cells byan scFv against the DNA-dependent protein kinase   [0163] 
Adenovirus-mediated heat-activated antisense Ku70 expression radiosensitizes tumor cells in vitro and in vivo   [0163] 
DNA repair and recombination factorRad51 is over-expressed in human pancreaticadenocarcinoma   [0163] 
Evidence of the involvement of p53 in gamma-radiation-induced DNA repair in human lymphoblasts.vint   [0163] 
Tranfert de gène pour modifier la réponse à la radiotherapie Cancer Radiother   [0163] 
A Ku80 fragment with dominant negative activity imparts a radiosensitive phenotype to CHO-K1 cells   [0163] 
Transfer of Ku80 RNA antisense decreases the radioresistance of human fibroblasts   [0163] 
DNA-dependent protein kinase catalytic subunit: structural requirements for kinase activity by DNA ends   [0163] 
Mechanism of interaction between Ku protein and DNA   [0163] 
DNA-PK and ATM are required for radiation-enhanced integration   [0163] 
Immunological disorders and DNA repair   [0163] 
In vitro and in vivo potentiation of radiosensitivity of malignant gliomas by antisense inhibition of the RAD51 gene   [0163] 
Ku proteins join DNA fragments as shown by atomic force microscopy   [0163] 
Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation   [0163] 
DNA double strand breaks (DSB) and non-homologous end joining (NHEJ) pathways in human leukemia   [0163] 
Genetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class switch recombination   [0163] 
Selective inactivation of DNA-dependent protein kinase with antisense oligodeoxynucleotides: consequences for the rejoining of radiation-induced DNA double-strand breaks and radiosensitivity of human cancer cell lines   [0163] 
Ionizing radiation greatly improves gene transfer efficiency in mammalian cells   [0163] 
Radiation-induced recombination is dependent on KU80   [0163] 
DNA damaging agents improve stable gene transfer efficiency in mammalian cells   [0163] 
Modulation de la réponse cellulaire aux radiations ionisantes: vers de nouvelles cibles moléculaires   [0163] 
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair   [0163] 
Characterization of the RNA binding properties of Ku protein   [0163] 
Photocross-linking of an oriented DNA repair complex. Ku bound at a single DNA end   [0163] 
Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein   [0163] 
The solution structure of the DNA double-stranded break repair protein Ku and its complex with DNA: a neutron contrast variation study   [0163]