Description  Claims  Drawing  Cited references 

US7419992B   [0070] 
US6916834B   [0070] 

2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity   [0071] 
Mechanistic aspects--the dioxin (aryl hydrocarbon) receptor   [0071] 
Ah receptor- and TCDD-mediated liver tumor promotion: clonal selection and expansion of cells evading growth arrest and apoptosis   [0071] 
The aryl hydrocarbon receptor: a perspective on potential roles in the immune system   [0071] 
Ah receptor signals cross-talk with multiple developmental pathways   [0071] 
Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers (Review)   [0071] 
The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth   [0071] 
A ligand for the aryl hydrocarbon receptor isolated from lung   [0071] 
The selective aryl hydrocarbon receptor modulator 6-methyl-1,3,8-trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice   [0071] 
Inhibition of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists   [0071] 
Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin   [0071] 
Tamoxifen-induced antitumorigenic/antiestrogenic action synergized by a selective aryl hydrocarbon receptor modulator   [0071] 
Correlation of in vitro and in vivo growth suppression of MCF-7 human breast cancer by 2,3,7,8-tetrachlorodibenzo-p-dioxin   [0071] 
The aryl hydrocarbon receptor as a target for estrogen receptor-negative breast cancer chemotherapy   [0071] 
Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands   [0071] 
Estimates of cancer potency of 2,3,7,8-tetrachlorodibenzo(p)dioxin using linear and nonlinear dose-response modeling and toxicokinetics   [0071] 
Activation of the aryl hydrocarbon receptor pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer   [0071] 
Activation of the aryl hydrocarbon receptor by TCDD inhibits senescence: a tumor promoting event?   [0071] 
Carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in experimental models   [0071] 
Antiangiogenic therapy and surgical practice   [0071] 
Current concerns and challenges regarding tailored anti-angiogenic therapy in cancer   [0071] 
VEGF inhibition and metastasis: possible implications for antiangiogenic therapy   [0071] 
Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited   [0071] 
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis   [0071] 
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis   [0071] 
Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor   [0071] 
A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo   [0071] 
The effect of aryl hydrocarbon receptor ligands on the expression of AhR, AhRR, ARNT, Hif1alpha, CYP1A1 and NQO1 genes in rat liver   [0071] 
Beta-naphthoflavone represses dystrophin Dp71 expression in hepatic cells   [0071] 
Toxic and chemopreventive ligands preferentially activate distinct aryl hydrocarbon receptor pathways: implications for cancer prevention   [0071] 
Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation   [0071] 
2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells   [0071] 
Altered cell cycle control at the G(2)/M phases in aryl hydrocarbon receptor-null embryo fibroblast   [0071] 
Role of the aryl hydrocarbon receptor in cell cycle regulation   [0071] 
The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phase-specific gene expression   [0071] 
Aryl hydrocarbon receptor-mediated apoptosis of neuronal cells: a possible interaction with estrogen receptor signaling   [0071] 
Primary peripheral T cells become susceptible to 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated apoptosis in vitro upon activation and in the presence of dendritic cells   [0071] 
The aryl hydrocarbon receptor predisposes hepatocytes to Fas-mediated apoptosis   [0071] 
Langerhans cell maturation and contact hypersensitivity are impaired in aryl hydrocarbon receptor-null mice   [0071] 
EGF receptor signaling blocks aryl hydrocarbon receptor-mediated transcription and cell differentiation in human epidermal keratinocytes   [0071] 
Activation of the Aryl-Hydrocarbon Receptor Inhibits Invasive and Metastatic Features of Human Breast Cancer Cells and Promotes Breast Cancer Cell Differentiation   [0071] 
TCDD and PCBs inhibit breast cancer cell proliferation in vitro   [0071] 
Cross-talk between 2,3,7,8-tetrachlorodibenzo-p-dioxin and testosterone signal transduction pathways in LNCaP prostate cancer cells   [0071] 
Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation   [0071] 
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins   [0071] 
Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer   [0071] 
Expression of the aryl hydrocarbon receptor (AhR) and the aryl hydrocarbon receptor nuclear translocator (ARNT) in fetal, benign hyperplastic, and malignant prostate   [0071] 
beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor   [0071] 
Potential therapeutic significance of increased expression of aryl hydrocarbon receptor in human gastric cancer   [0071]