Description  Claims  Drawing  Cited references 

WO2008079371A   [0005] 

Bioorganic & Medicinal Chemistry Letters   [0006] 
FASEB J.   [0008] 
Protective Groups in Organic Synthesis   [0058] 
Deletion of the complement anaphylatoxin C3a receptor attenuates, whereas ectopic expression of C3a in the brain exacerbates, experimental autoimmune encephalomyelitis   [0342] 
C3a expressed in the central nervous system protects against LPS-induced shock   [0342] 
Cutting edge: the absence of C3 demonstrates a role for complement in Th2 effector functions in a murine model of pulmonary allergy   [0342] 
Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy   [0342] 
Weight gain in relation to plasma levels of complement factor 3: results from a population-based cohort study   [0342] 
Synergistic neuroprotective effects of C3a and C5a receptor blockade following intracerebral hemorrhage   [0342] 
Synthesis of IB-01211, a cyclic peptide containing 2,4-concatenated thia- and oxazoles, via Hantzsch macrocyclization   [0342] 
A role for the C3a anaphylatoxin receptor in the effector phase of asthma   [0342] 
Effect of the C3a-receptor antagonist SB 290157 on anti-OVA polyclonal antibody-induced arthritis   [0342] 
C3aR inhibition reduces neurodegeneration in experimental lupus   [0342] 
The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen   [0342] 
Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock   [0342] 
Targeting complement in therapy   [0342] 
Antimicrobial C3a - Biology, biophysics, and evolution   [0342] 
The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation   [0342] 
The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation   [0342] 
Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease   [0342] 
Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice   [0342] 
Complement component C3 mediates inflammatory injury following focal cerebral ischemia   [0342] 
Ablation of the complement C3a anaphylatoxin receptor causes enhanced killing of Pseudomonas aeruginosa in a mouse model of pneumonia   [0342] 
Activation of the complement system generates antibacterial peptides   [0342] 
The metabolic syndrome in relation to complement component 3 and postprandial lipemia in patients from an outpatient lipid clinic and healthy volunteers   [0342] 
Rational Design of Antimicrobial C3a Analogues with Enhanced Effects against Staphylococci Using an Integrated Structure and Function-Based Approach   [0342] 
Bioisosterism: A rational approach in Drug Design   [0342] 
C3a-derived peptide binds to the type I Fc epsilon R and inhibits proximal-coupling signal processes and cytokine secretion by mast cells   [0342] 
Arginine Mimetics   [0342] 
Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome   [0342] 
Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor   [0342] 
Complement: a novel factor in basal and ischemia-induced neurogenesis   [0342] 
C3a receptor antagonist attenuates brain injury after intracerebral hemorrhage   [0342] 
Antifungal activity of C3a and C3a-derived peptides against Candida   [0342] 
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy   [0342] 
Rational design of bacitracin A derivatives by incorporating natural product derived heterocycles   [0342] 
C3a receptor deficiency accelerates the onset of renal injury in the MRL/lpr mouse   [0342] 
Complement regulators and inhibitory proteins   [0342]