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An integrated encyclopedia of DNA elements in the human genome   [0414] 
Core transcriptional regulatory circuitry in human embryonic stem cells   [0414] 
Histone H3K27ac separates active from poised enhancers and predicts developmental state   [0414] 
Cdx2 gene expression and trophectoderm lineage specification in mouse embryos   [0414] 
Topological domains in mammalian genomes identified by analysis of chromatin interactions   [0414]  [0522] 
Dissecting self-renewal in stem cells with RNA interference   [0414] 
Mediator and cohesin connect gene expression and chromatin architecture   [0414]  [0522]  [0522] 
The miR-290-295 cluster promotes pluripotency maintenance by regulating cell cycle phase distribution in mouse embryonic stem cells   [0414] 
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation   [0414] 
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells   [0414] 
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells   [0414] 
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells   [0414] 
Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation   [0414] 
Enhancer function: new insights into the regulation of tissue-specific gene expression   [0414] 
A unique chromatin signature uncovers early developmental enhancers in humans   [0414] 
Linking disease associations with regulatory information in the human genome   [0414] 
A map of the cis-regulatory sequences in the mouse genome   [0414]  [0522] 
Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst   [0414] 
The accessible chromatin landscape of the human genome   [0414]  [0522] 
Brgl is required for Cdx2-mediated repression of Oct4 expression in mouse blastocysts   [0414] 
Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors   [0414] 
Control of the embryonic stem cell state   [0414]  [0522] 
Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells   [0414] 
Members of the miR-290 cluster modulate in vitro differentiation of mouse embryonic stem cells   [0414] 
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription   [0431] 
The enhanceosome and transcriptional synergy   [0431]  [0522] 
A potent GAL4 derivative activates transcription at a distance in vitro   [0431] 
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia   [0431] 
BET bromodomain inhibition as a therapeutic strategy to target c-Myc   [0431] 
Histone recognition and large-scale structural analysis of the human bromodomain family   [0431] 
Selective inhibition of BET bromodomains   [0431] 
Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions   [0431] 
Cooperative DNA binding of the yeast transcriptional activator GAL4   [0431] 
Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression   [0431] 
Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation   [0431] 
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription   [0431] 
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways   [0431] 
The mechanism of transcriptional synergy of an in vitro assembled interferon-beta enhanceosome   [0431] 
Targeting MYC dependence in cancer by inhibiting BET bromodomains   [0431] 
X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors   [0431] 
Suppression of inflammation by a synthetic histone mimic   [0431] 
IRF4 addiction in multiple myeloma   [0431] 
Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome   [0431] 
The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation   [0431] 
Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors   [0431] 
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4   [0431] 
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia   [0431] 
Nucleic Acids Research   [0508] 
Nat. Rev. Cancer   [0508] 
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC   [0522]  [0522] 
Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses   [0522] 
The molecular genetics of cancer   [0522] 
Genetics, pathogenesis and clinical interventions in type 1 diabetes   [0522] 
Developmental regulation of eukaryotic gene loci: which cis-regulatory information is required?   [0522]  [0522] 
Core transcriptional regulatory circuitry in human embryonic stem cells   [0522] 
Functional and mechanistic diversity of distal transcription enhancers   [0522] 
Modification of enhancer chromatin: what, how, and why?   [0522] 
Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology   [0522] 
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells   [0522] 
Reprogramming cellular identity for regenerative medicine   [0522] 
Genetics and epigenetics of systemic lupus erythematosus   [0522] 
Histone H3K27ac separates active from poised enhancers and predicts developmental state   [0522] 
Genetic susceptibility to systemic lupus erythematosus in the genomic era   [0522] 
The human Mi-2/NuRD complex and gene regulation   [0522] 
An integrated encyclopedia of DNA elements in the human genome   [0522] 
A genetic model for colorectal tumorigenesis   [0522] 
COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer   [0522]  [0522] 
A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus   [0522] 
Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability   [0522] 
A census of human cancer genes   [0522] 
Lessons from the cancer genome   [0522] 
Forcing cells to change lineages   [0522] 
Identifying recent adaptations in large-scale genomic data   [0522] 
Position-independent, high-level expression of the human beta-globin gene in transgenic mice   [0522] 
Hallmarks of cancer: the next generation   [0522] 
Histone modifications at human enhancers reflect global cell-type-specific gene expression   [0522] 
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome   [0522] 
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits   [0522] 
An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network   [0522] 
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency   [0522] 
Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer   [0522]  [0522] 
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription   [0522] 
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways   [0522] 
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells   [0522] 
Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells   [0522] 
Widespread transcription at neuronal activity-regulated enhancers   [0522] 
Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters   [0522]  [0522] 
Activating RNAs associate with Mediator to enhance chromatin architecture and transcription   [0522] 
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription   [0522] 
Transcriptional regulation and its misregulation in disease   [0522] 
Disentangling the many layers of eukaryotic transcriptional regulation   [0522] 
Transcription regulation and animal diversity   [0522] 
Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation   [0522] 
HS2 enhancer function is blocked by a transcriptional terminator inserted between the enhancer and the promoter   [0522] 
Selective inhibition of tumor oncogenes by disruption of super-enhancers   [0522] 
Transcriptional regulatory elements in the human genome   [0522] 
Systematic localization of common disease-associated variation in regulatory DNA   [0522]  [0522] 
Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription   [0522] 
eRNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci   [0522] 
Master transcription factors determine cell-type-specific responses to TGF-beta signaling   [0522]  [0522] 
Noncoding transcription at enhancers: general principles and functional models   [0522] 
An expansive human regulatory lexicon encoded in transcription factor footprints   [0522] 
The transcriptional and signalling networks of pluripotency   [0522] 
Genetics of type 1 diabetes   [0522] 
Enhancer function: new insights into the regulation of tissue-specific gene expression   [0522] 
Chromatin connections to pluripotency and cellular reprogramming   [0522] 
Long noncoding RNAs with enhancer-like function in human cells   [0522] 
The enhanceosome   [0522] 
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer   [0522]  [0522] 
A unique chromatin signature uncovers early developmental enhancers in humans   [0522] 
NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment   [0522] 
NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression   [0522] 
CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression   [0522] 
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1   [0522] 
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells   [0522]  [0522] 
Transcription factors: from enhancer binding to developmental control   [0522] 
The genetics of Alzheimer disease   [0522] 
The ''beta-like-globin'' gene domain in human erythroid cells   [0522] 
Personal and population genomics of human regulatory variation   [0522] 
ChIP-seq accurately predicts tissue-specific activity of enhancers   [0522] 
Cancer genome landscapes   [0522] 
Enhancer decommissioning by LSD1 during embryonic stem cell differentiation   [0522]  [0522] 
Master transcription factors and mediator establish super-enhancers at key cell identity genes   [0522]  [0522] 
Developmental biology. Enhancing pluripotency and lineage specification   [0522]  [0522] 
Model-based analysis of ChIP-Seq (MACS)   [0522]  [0522] 
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells   [0522] 
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions   [0522] 
bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS   [0522] 
Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system   [0522] 
Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation   [0522] 
Sequentially acting Sox transcription factors in neural lineage development   [0522] 
Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression   [0522] 
The NIH Roadmap Epigenomics Mapping Consortium   [0522] 
The role of SOX10 during enteric nervous system development   [0522] 
Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling   [0522] 
The transcription factor Sox10 is a key regulator of peripheral glial development   [0522] 
Transcriptional control of early B cell development   [0522] 
T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis   [0522] 
Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis   [0522] 
Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-t1 cells   [0522] 
Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants   [0522] 
Expression of a single transfected cDNA converts fibroblasts to myoblasts   [0522] 
Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells   [0522] 
Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation   [0522] 
Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain   [0522] 
Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation   [0522] 
FIMO: scanning for occurrences of a given motif   [0522] 
Six 1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype   [0522] 
The B cell coactivator Bob1 shows DNA sequence-dependent complex formation with Oct-1/Oct-2 factors, leading to differential promoter activation   [0522] 
Direct reprogramming of fibroblasts into neural stem cells by defined factors   [0522] 
Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation   [0522] 
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors   [0522] 
Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex   [0522] 
Bach2: plasma-cell differentiation takes a break   [0522] 
The human genome browser at UCSC   [0522] 
Aiolos: an ungrateful member of the Ikaros family   [0522] 
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome   [0522] 
Identification of direct regulatory targets of the transcription factor Sox10 based on function and conservation   [0522] 
The many faces of PPARgamma   [0522] 
Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis   [0522] 
Transcriptional amplification in tumor cells with elevated c-Myc   [0522] 
Cistrome: an integrative platform for transcriptional regulation studies   [0522] 
Selective inhibition of tumor oncogenes by disruption of super-enhancers   [0522] 
Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b   [0522] 
Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5   [0522] 
Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression   [0522] 
C/EBPalpha is required for lung maturation at birth   [0522] 
TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes   [0522] 
Transcriptional regulation of cortical neuron migration by POU domain factors   [0522] 
Pax5: a master regulator of B cell development and leukemogenesis   [0522] 
An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation   [0522] 
Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor   [0522] 
Transcription factor-induced lineage selection of stem-cell-derived neural progenitor cells   [0522] 
Direct conversion of human fibroblasts to dopaminergic neurons   [0522] 
NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins   [0522] 
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes   [0522] 
CREB activation induces adipogenesis in 3T3-L1 cells   [0522] 
Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor   [0522] 
PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro   [0522] 
Transcriptional regulation of adipogenesis   [0522] 
MyoD or Myf-5 is required for the formation of skeletal muscle   [0522] 
Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia   [0522] 
A census of amplified and overexpressed human cancer genes   [0522] 
TcoF-DB: dragon database for human transcription co-factors and transcription factor interacting proteins   [0522] 
The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs   [0522] 
Re-expression of GATA2 cooperates with peroxisome proliferator-activated receptor-gamma depletion to revert the adipocyte phenotype   [0522] 
Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma   [0522] 
Conversion of mouse and human fibroblasts into functional spinal motor neurons   [0522] 
Heart repair by reprogramming non-myocytes with cardiac transcription factors   [0522] 
Brn-I and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons   [0522] 
Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD   [0522] 
Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development   [0522] 
Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene   [0522] 
RSAT 2011: regulatory sequence analysis tools   [0522] 
TopHat: discovering splice junctions with RNA-Seq   [0522] 
GATA factors efficiently direct cardiac fate from embryonic stem cells   [0522] 
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis   [0522] 
Molecular principles of Oct2-mediated gene activation in B cells   [0522] 
Six family genes control the proliferation and differentiation of muscle satellite cells   [0522] 
AnimalTFDB: a comprehensive animal transcription factor database   [0522]