Description     Claims     Drawing  

CA152194   [0001] 
WO2012149049A1   [0008] 
US2011028474A1   [0009] 

describe the therapeutic potential of targeting the oncogenic SHP2 Phosphatase   [0006] 
describe a facile hydroxyindole carboxylic acid based focused library approach for potent and selective inhibitors of mycobacterium protein tyrosine phosphatase B   [0007] 
describe a salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2)   [0010] 
describe small molecule tools for functional interrogation of protein tyrosine phosphatases   [0011] 
Salicylic acid-based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2)   [0093]  [0112] 
HKL-3000: the integration of data reduction and structure solution ··· from diffraction images to an initial model in minutes   [0107] 
MOLREP: an automated program for molecular replacement   [0108] 
Large-scale structural analysis of the classical human protein tyrosine phosphatome   [0108]  [0112] 
Crystallography & NMR system: a new software suite for macro-molecular structure determination   [0108] 
Salicylic acid-based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tryosine phosphatase-2 (SHP2)   [0111] 
AutoDock 4 and AutoDock Tools4: Automated Docking with Selective Receptor Flexibility   [0112] 
Python: A programming language for software integration and development   [0112] 
Targeting SHP2 for EGFR inhibitor resistant non-small cell lung carcinoma   [0118] 
Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT   [0131]