Description     Claims     Drawing  

US7825090B   [0003]  [0022] 
US7485620B   [0003]  [0022] 
US7666833B   [0003]  [0022] 
US8071368B   [0003]  [0022] 
US8222217B   [0003]  [0022] 
US8318664B   [0003] 
US8476408B   [0003]  [0022] 
US20100016226A   [0003]  [0004]  [0022] 
US20130157936A   [0003]  [0022] 
WO2009150214A   [0003]  [0004] 
WO2013088241A   [0003] 
US8318666B   [0022] 
WO61837723A   [0082] 

Solid Phase Peptide Synthesis   [0032] 
Solid Phase Peptide Synthesis   [0032] 
Peptide synthesis protocols   [0032] 
Solid phase peptide synthesis   [0032] 
The Proteins   [0032] 
Ghrelin is a growth-hormone-releasing acylated peptide from stomach   [0081] 
The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans   [0081] 
A receptor in pituitary and hypothalamus that functions in growth hormone release   [0081] 
Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans   [0081] 
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats   [0081] 
Ghrelin is a growth-hormone-releasing acylated peptide from stomach   [0081] 
Ghrelin induces adiposity in rodents   [0081] 
The endocrine response to acute ghrelin administration is blunted in patients with anorexia nervosa, a ghrelin hypersecretory state   [0081] 
Ghrelin suppresses glucose-stimulated insulin secretion and deteriorates glucose tolerance in healthy humans   [0081] 
Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin   [0081] 
Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin   [0081] 
Non-acylated ghrelin counteracts the metabolic but not the neuroendocrine response to acylated ghrelin in humans   [0081] 
Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity   [0081] 
Effects of acute administratio of acylated and unacylated ghrelin on glucose and insulin concentratios in morbidly obese subjects without overt diabetes   [0081] 
Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes   [0081] 
Unacylated ghrelin acts as a potent insulin secretagogue in glucose-stimulated conditions   [0081] 
Oxidative damage pathways in relation to normal tissue injury   [0081] 
Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells   [0081] 
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT   [0081] 
Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes   [0081] 
Ghrelin, des-acyl ghrelin and obestatin: three pieces of the same puzzle   [0081] 
Des-acyl ghrelin has specific binding sites and different metabolic effects from ghrelin in cardiomyocytes   [0081] 
Unacylated ghrelin rescues endothelial progenitor cell function in individuals with type 2 diabetes   [0081] 
Des-acyl ghrelin fragments and analogues promote survival of pancreatic β-cells and human pancreatic islets and prevent diabetes in streptozotocin-treated rats   [0081] 
Diagnosis and treatment of chronic arterial insufficiency of the lower extremities: a critical review   [0081] 
American Heart Association Writing Group 7. Atherosclerotic Peripheral Vascular Disease Symposium II: lower-extremity revascularization: state of the art   [0081] 
Functional ability in patients with critical limb ischaemia is unaffected by successful revascularisation   [0081] 
The myopathy of peripheral arterial occlusive disease: Part 2. Oxidative stress, neuropathy, and shift in muscle fiber type   [0081] 
Skeletal muscle mitochondrial DNA injury in patients with unilateral peripheral arterial disease   [0081] 
Radical medicine: treating ageing to cure disease   [0081] 
Mitochondrial Dysfunction in Atherosclerosis   [0081] 
p66ShcA modulates tissue response to hindlimb ischemia   [0081] 
p66(ShcA) and oxidative stress modulate myogenic differentiation and SMR after hind limb ischemia   [0081] 
Muscle mitochondrial function in patients with type 2 diabetes mellitus and peripheral arterial disease: implications in vascular surgery   [0081] 
Oxidative-stress-mediated arterial dysfunction in patients with peripheral arterial disease   [0081] 
The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell   [0081] 
Coordination of satellite cell activation and self-renewal by Par-complex-dependent asymmetric activation of p38α/β MAPK   [0081] 
Acute skeletal muscle injury: CCL2 expression by both monocytes and injured muscle is required for repair   [0081] 
PYY in the regulation of energy balance and metabolism: lessons from mouse mutants   [0081] 
Microrna-221 and microrna-222 modulate differentiation and maturation of skeletal muscle cells   [0081] 
Deregulated microRNAs in myotonic dystrophy type 2   [0081] 
Variations in surgical procedures for hind limb ischaemia mouse models result in differences in collateral formation   [0081] 
Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia   [0081] 
Interleukin-3 promotes expansion of hemopoietic-derived CD45+ angiogenic cells and their arterial commitment via STAT5 activation   [0081] 
Isolation and culture of mouse satellite cells   [0081] 
IL-3 is a novel target to interfere with tumor vasculature   [0081] 
MIR221/MIR222-driven posttranscriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGEmediated vascular cell damage   [0081] 
microRNA-222 controls neovascularization by regulating signal transducer and activator of transcription 5A expression   [0081] 
Mechanisms in endocrinology: Ghrelin: the differences between acyl- and des-acyl ghrelin   [0081] 
Des-Acyl ghrelin fragments and analogues promote survival of pancreatic b-cells and human pancreatic islets and prevent diabetes in streptozotocin-treated rats   [0081]