Pharmaceutical Salts
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Pharmaceutical Dosage Forms
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The Art, Science and Technology of Pharmaceutical Compounding
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Dosage Calculations
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Remington: The Science and Practice of Pharmacy
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J. Biomater Sci. Polym. Ed.
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Pharm. Res.
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J. Pharm. Pharmacol.
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J. Microencapsul.
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Curr. Opin. Biotechnol.
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Am. J. Hosp. Pharm.
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THE PHARMACOLOGICAL BASIS OF THERAPEUTICS
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Pharmaceutical Sciences
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Remington's Pharmaceutical Sciences
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Nat. Med.
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JNM
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Structure and function of cellular deoxyribonucleoside kinases
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Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
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Requirement for deoxycytidine kinase in T and B lymphocyte development
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Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress
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A deficiency in nucleoside salvage impairs murine lymphocyte development, homeostasis, and survival
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Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage
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Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication
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Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography
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Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules
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Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization
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Structural basis for substrate promiscuity of dCK
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Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery
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Rearrangement of Acetylenic Keto Alcohols under Meyer-Schuster Reaction Conditions
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Solution-phase parallel synthesis with oligoethylene glycol sorting tags. Preparation of all four stereoisomers of the hydroxybutenolide fragment of murisolin and related acetogenins
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Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications
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Comparison of Simple Potential Functions for Simulating Liquid Water
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Development and testing of the OPLS all-atom force field on conformational energetics and properties of organic liquids
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Molecular modeling of organic and biomolecular systems using BOSS and MCPRO
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Free energies of hydration from a generalized Born model and an ALL-atom force field
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PDDG/PM3 and PDDG/MNDO: improved semiempirical methods
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Semianalytical Treatment of Solvation for Molecular Mechanics and Dynamics
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Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-nucleosides
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Guanylate kinases from human erythrocytes, hog brain, and rat liver
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MULTI-FORTE, a microcomputer program for modelling and simulation of pharmacokinetic data
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a simulation and modeling program for pharmacokinetic and pharmacodynamic data analysis
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Acta Crystallogr D Biol Crystallogr
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Teplyakov, A. Molecular replacement with MOLREP
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REFMAC5 for the refinement of macromolecular crystal structures
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Features and development of Coot
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a tool for high-throughput crystallography of protein-ligand complexes
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Molecular modeling of organic and biomolecular systems using BOSS and MCPRO
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Improved semiempirical heats of formation through the use of bond and group equivalents
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Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress
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Thresholds of replication stress signaling in cancer development and treatment
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Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemia
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Clinical phase I-II and pharmacokinetic study of high-dose thymidine given by continuous intravenous infusion
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Simultaneous analysis of eight nucleoside triphosphates in cell lines by liquid chromatography coupled with tandem mass spectrometry
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Activation of deoxycytidine kinase by gamma-irradiation and inactivation by hyperosmotic shock in human lymphocytes
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Kinetic properties and inhibition of human T lymphoblast deoxycytidine kinase
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Translating cancer research into targeted therapeutics
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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
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Hallmarks of cancer: the next generation
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DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation
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Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation
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Characterization of a gemcitabine-resistant murine leukemic cell line: reversion of in vitro resistance by a mononucleotide prodrug
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Liquid chromatography-high resolution mass spectrometry analysis of fatty acid metabolism
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High-dose thymidine infusions in patients with leukemia and lymphoma
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Effect of high-dose thymidine infusions in patients with mycosis fungoides
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Principles of cancer therapy: oncogene and non-oncogene addiction
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Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
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Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography
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Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules
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Role of thymidine in biochemical modulation: a review
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Increased deoxycytidine kinase activity by etoposide in L1210 murine leukemic cells
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Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2'-deoxycytidine analog
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Interactions between deoxyribonucleotide and DNA synthesis
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[0432]
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Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR
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Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway
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Imaging proliferation in vivo with [F-18]FLT and positron emission tomography
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Novel PET probes specific for deoxycytidine kinase
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Cyclodextrins. Toxicologic pathology
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Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo
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Requirement for deoxycytidine kinase in T and B lymphocyte development
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Targeting cancer metabolism: a therapeutic window opens
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The Metabolism of Tumors in the Body
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Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia
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Functional compartmentation of dCTP pools. Preferential utilization of salvaged deoxycytidine for DNA repair in human lymphoblasts
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Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage
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Novel Potent Inhibitors of Deoxycytidine Kinase Identified and Compared by Multiple Assays
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Mammalian Deoxyribonucleoside Kinases
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Structural Basis for Substrate Promiscuity of dCK
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Reaction of Human UMP-CMP Kinase with Natural and Analog Substrates
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Novel Role of 3-Phosphoglycerate Kinase, a Glycolytic Enzyme, in the Activation of L-Nucleoside Analogs, a new class of Anticancer and Antiviral Agents
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Requirement for Deoxycytidine Kinase in T and B Lymphocyte Development
| [0432]
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Nucleoside Salvage Pathway Kinases Regulate Hematopoiesis by Linking Nucleotide Metabolism with Replication Stress
| [0432]
|
Substrate Specificity and Phosphorylation of Antiviral and Anticancer Nucleoside Analogs by Human Deoxyribonucleoside Kinases and Ribonucleoside Kinases
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Deoxycytidine kinase regulates the G2/M checkpoint through interaction with cyclin-dependent kinase 1 in response to DNA damage
| [0432]
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5-Fluorocytosine Derivatives as Inhibitors of Deoxycytidine Kinase
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Novel Potent Inhibitors of Deoxycytidine Kinase Identified and Compared by Multiple Assays
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Irreversible Enzyme Inhibitors: Active-Site-Directed Inhibitors of Deoxycytidine Kinase
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Lead Optimization and Structure-based Design of Potent and Bioavailable Deoxycytidine Kinase Inhibitors
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Technology Insight: Advances in Molecular Imaging and an Appraisal of PET/CT Scanning
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PET/CT Imaging: The Incremental Value of Assessing the Glucose Metabolic Phenotype and the Structure of Cancers in a Single Examination
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Molecular Imaging of Cancer with Positron Emission Tomography
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Oncological Application of Positron Emission Tomography with Fluorine-18
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Positron Emission Tomography in Oncology: A Review
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Positron Emission Tomography as an Imaging Biomarker
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Present Role and Future Prospects of Positron Emission Tomography in Clinical Oncology
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18F-FDG Uptake in Lung, Breast, and Colon Cancers: Molecular Biology Correlates and Disease Characterization
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The Role of Molecular Imaging in Drug Discovery and Development
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Positron Emission Tomography: Applications in Drug Discovery and Drug Development
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Positron Emission Tomography for Use in Microdosing Studies
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Noninvasive Prediction of Tumor Responses to Gemcitabine using Positron Emission Tomography
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Molecular Imaging of Lymphoid Organs and Immune Activation by Positron Emission Tomography with a new [18F]-labeled 2'-deoxycytidine Analog
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Novel PET Probes Specific for Deoxycytidine Kinase
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Bioluminescent assays for high-throughput screening
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Fluorine in Pharmaceuticals: Looking Beyond Intuition
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Metabolsim of Fluorine-containing
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Reactions of Some Ortho and Para Halogenated Aromatic Nitriles with Ethylenediamine: Selective Synthesis of Imidazolines
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Synthesis of 2-Oxazolone-4-Carboxylates from 3-Nosyloxy- and 3-Bromo-2-ketoesters
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Synthesis of Benzyl Bromides with Hexabromoacetone: an Alternative Path to Drug Intermediates
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15N5)-Labeled Adenine Derivatives: Synthesis and Studies of Tautomerism by 15N NMR Spectroscopy and Theoretical Calculations
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Cloning and Expression of Human Deoxycytidine Kinase cDNA
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Nucleotide Specificity of Human Deoxycytidine Kinase
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The Monte Carlo Method
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High-Temperature Equation of State by a Perturbation Method
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Perspective on Free-Energy Perturbation Calculations for Chemical Equilibria
| [0432]
|
Molecular Modeling of Organic and Biomolecular Systems Using BOSS and MCPRO
| [0432]
|
Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery
| [0432]
|
Application of Positron Emission Tomography in Drug Development
| [0432]
|
Comparison of Simple Potential Functions for Simulating Liquid Water
| [0432]
|
Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids
| [0432]
|