Description  Claims  Drawing  Cited references 

WO2011140114A   [0008]  [0088]  [0126] 
WO2013066876A   [0008]  [0088] 
US6596509B   [0031] 
US5750373A   [0058] 
US5545807A   [0058] 
US5545806A   [0058] 
US5569825A   [0058] 
US5625126A   [0058] 
US5633425A   [0058] 
US5661016A   [0058] 
US4816567A   [0070] 
US4237224A   [0077] 
US20130110249A   [0135]  [0138] 
US61915953B   [0139] 

Treatment of Infections Associated With Surgical Implants   [0002]  [0004] 
Rates and Outcomes of Primary and Revision Total Hip Replacement in the United States Medicare Population   [0002]  [0002] 
Osteomyelitis   [0002] 
The Management of Peri-Prosthetic Infection in Total Joint Arthroplasty   [0002] 
Outcome of a Second Two-stage Reimplantation for Periprosthetic Knee Infection   [0002] 
Cloning and Expression of the Gene for a Fibronectin-Binding Protein from Staphylococcus aureus   [0004] 
Surface-Associated Proteins from Staphylococcus aureus Demonstrate Potent Bone Resorbing Activity   [0004] 
Osteoblasts Express the Inflammatory Cytokine Interleukin-6 in a Murine Model of Staphylococcus aureus Osteomyelitis and Infected Human Bone Tissue   [0004]  [0006] 
Bacterial Biofilms: A Common Cause of Persistent Infections   [0004]  [0006] 
Effect of Extracellular Slime Substance from Staphylococcus epidermidis on the Human Cellular Immune Response   [0004] 
Interference with Granulocyte Function by Staphylococcus epidermidis Slime   [0004] 
Antibiotic Resistance of Biomaterial-Adherent Coagulase-Negative and Coagulase-Positive Staphylococci   [0004] 
Involvement of Mitogen-Activated Protein Kinase Pathways in Staphylococcus aureus Invasion of Normal Osteoblasts   [0005] 
In Vivo Internalization of Staphylococcus aureus by Embryonic Chick Osteoblasts   [0005] 
Persistent and Relapsing Infections Associated with Small-Colony Variants of Staphylococcus aureus   [0005] 
Resistance of Staphylococcus aureus Recovered From Infected Foreign Body in Vivo to Killing by Antimicrobials   [0005] 
Long-Bone Osteomyelitis Diagnosis and Management   [0005] 
Lessons Learned from Animal Models of Osteomyelitis   [0006] 
A Model of Staphylococcus aureus Bacteremia, Septic Arthritis, and Osteomyelitis in Chickens   [0006] 
Model of Experimental Chronic Osteomyelitis in Rats   [0006] 
A Model of Experimental Post-Traumatic Osteomyelitis in Guinea Pigs   [0006] 
An Experimental Model of Post-Traumatic Osteomyelitis in Rabbits   [0006] 
Experimental Model of Staphylococcal Osteomyelitis in Dogs   [0006] 
New Model for Chronic Osteomyelitis With Staphylococcus aureus in Sheep   [0006] 
Susceptibility of Staphylococcus aureus Growing on Fibronectin-Coated Surfaces to Bactericidal Antibiotics   [0006] 
Binding of a Staphylococcus aureus Bone Pathogen to Type I Collagen   [0006] 
A Collagen Receptor on Staphylococcus aureus Strains Isolated From Patients With Septic Arthritis Mediates Adhesion to Cartilage   [0006] 
Quorum Sensing in Staphylococcus aureus Biofilms   [0007] 
MSCRAMM-Mediated Adherence of Microorganisms to Host Tissues   [0007] 
Journal of Bacteriology   [0010] 
Journal of Bacteriology   [0010] 
PLoS One   [0010] 
Passive Immunization With Anti-Glucosaminidase Monoclonal Antibodies Protects Mice From Implant-Associated Osteomyelitis by Mediating Opsonophagocytosis of Staphylococcus aureus Megaclusters   [0020]  [0039] 
Targeting of Muralytic Enzymes to the Cell Division Site of Gram-Positive Bacteria: Repeat Domains Direct Autolysin to the Equatorial Surface Ring of Staphylococcus aureus   [0027] 
An Autolysin Ring Associated With Cell Separation of Staphylococcus aureus   [0027] 
Targeting of Muralytic Enzymes to the Cell Division Site of Gram-Positive Bacteria: Repeat Domains Direct Autolysin to the Equatorial Surface Ring of Staphylococcus aureus   [0028] 
Subcellular Localization of the Major Autolysin, ATL and Its Processed Proteins in Staphylococcus aureus   [0028] 
A Staphylococcus aureus Autolysin That Has an N-acetylmuramoyl-L-alanine Amidase Domain and an Endo-beta-N-acetylglucosaminidase Domain: Cloning, Sequence Analysis, and Characterization   [0028] 
Molecular Cloning: A Laboratory Manual   [0030] 
Monitoring Bioluminescent Staphylococcus aureus Infections in Living Mice Using a Novel luxABCDE Construct   [0037] 
Photonic Detection of Bacterial Pathogens in Living Hosts   [0037] 
Distinction of Epitopes by Monoclonal Antibodies   [0046] 
Analysis of the Fine Specificity and Cross-reactivity of Monoclonal Anti-lipid A Antibodies   [0046] 
Monoclonal Antibodies to Bovine Serum Albumin: Affinity and Specificity Determinations   [0046] 
Epitope-Specific Antibody Response to the Surface. Antigen of Duck Hepatitis B Virus in Infected Ducks   [0046] 
Identity of HML-1 Antigen on Intestinal Intraepithelial T Cells and of B-ly7 Antigen on Hairy Cell Leukaemia   [0046] 
Replacing the Complementarity-Determining Regions in a Human Antibody With Those From a Mouse   [0057] 
Reshaping Human Antibodies for Therapy   [0057] 
Reshaping Human Antibodies: Grafting an Antilysozyme Activity   [0057] 
Human Antibodies with Sub-Nanomolar Affinities Isolated from a Large Non-immunized Phage Display Library   [0058] 
Efficient Construction of a Large Nonimmune Phage Antibody Library: The Production of High-Affinity Human Single-Chain Antibodies to Protein Antigens   [0058] 
By-passing Immunisation. Human Antibodies from Synthetic Repertoires of Germline VH Gene Segments Rearranged in vitro   [0058] 
By-passing Immunization. Human Antibodies from V-gene Libraries Displayed on Phage   [0058] 
Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities   [0059] 
Enhanced Half-life of Genetically Engineered Human IgG1 Antibodies in a Humanized FcRn Mouse Model: Potential Application in Humorally Mediated Autoimmune Disease   [0060] 
Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification   [0060] 
Protein Engineering of Antibody Binding Sites: Recovery of Specific Activity in an Anti-Digoxin Single-Chain Fv Analogue Produced in Escherichia coli   [0062] 
Single-Chain Antigen-Binding Proteins   [0062] 
The Fibronectin Type III Domain as a Scaffold for Novel Binding Proteins   [0065] 
Probing Protein Conformational Changes in Living Cells by Using Designer Binding Proteins: Application to the Estrogen Receptor   [0065] 
Binding Proteins Selected from Combinatorial Libraries of an alpha-helical Bacterial Receptor Domain   [0065] 
Derivation of Specific Antibody-Producing Tissue Culture and Tumor Lines by Cell Fusion   [0068] 
Phage Antibodies: Filamentous Phage Displaying Antibody Variable Domains   [0070] 
Making Antibody Fragments using Phage Display Libraries   [0070] 
By-Passing Immunization. Human Antibodies from V-Gene Libraries Displayed on Phage   [0070] 
The Codon Preference Plot: Graphic Analysis of Protein Coding Sequences and Prediction of Gene Expression   [0071] 
Dual Asymetric PCR: One-Step Construction of Synthetic Genes   [0072] 
Site-Directed Mutagenesis of Virtually any Plasmid by Eliminating a Unique Site   [0073] 
Rapid and Efficient Site-Specific Mutagenesis Without Phenotypic Selection   [0073] 
Rapid and Efficient Site-Specific Mutagenesis Without Phenotypic Selection   [0073]  [0075] 
Maximizing Gene Expression on a Plasmid Using Recombination in vitro   [0080] 
Contribution of the Staphylococcus aureus Atl AM and GL Murein Hydrolase Activities in Cell Division, Autolysis, and Biofilm Formation   [0126] 
Secreted Proteases Control Autolysin-mediated Biofilm Growth of Staphylococcus aureus   [0126] 
Essential Role for the Major Autolysin in the Fibronectin-binding Protein-mediated Staphylococcus aureus Biofilm Phenotype   [0126] 
From Koch's Postulates to Biofilm Theory: The Lesson of Bill Costerton   [0126] 
The Calgary Biofilm Device: New Technology for Rapid Determination of Antibiotic Susceptibilities of Bacterial Biofilms   [0126] 
Quantitative Mouse Model of Implant-associated Osteomyelitis and the Kinetics of Microbial Growth, Osteolysis, and Humoral Immunity   [0129] 
Effects of Antiresorptive Agents on Osteomyelitis: Novel Insights into the Pathogenesis of Osteonecrosis of the Jaw   [0130] 
Quantitative Mouse Model of Implant-Associated Osteomyelitis and the Kinetics of Microbial Growth, Osteolysis, and Humoral Immunity   [0130] 
Genetic Requirements for Staphylococcus aureus Abscess Formation and Persistence in Host Tissues   [0132] 
Contribution of Coagulases Towards Staphylococcus aureus Disease and Protective Immunity   [0132] 
Protective and Pathogenic Functions of Macrophage Subsets   [0132] 
Efficient Generation of Monoclonal Antibodies from Single Human B Cells by Single Cell RT-PCR and Expression Vector Cloning   [0133]  [0136]