Description  Claims  Cited references 

US62106465   [0001] 
WO2013109972A2PCT   [0231] 
WO20130725PCT   [0231] 
WO2010089580A1PCT   [0231] 
WO20100812PCT   [0231] 

Synthesis and antitumor activity evaluation of chrysin derivatives   [0012] 
Quantitative structural-activity relationship study and directed synthesis of Thieno[2,3-d]pyrimidine-2,4-diones as monocarboxylate transporter 1 inhibitors   [0013] 
Potent blockers of the monocarboxylate transporter MCT1: Novel immunomodulatory compounds   [0014] 
Synthesis and Structure-Activity Relationships of Pteridine Dione and Trione Monocarboxylate Transporter 1 Inhibitors   [0015] 
Protective Groups in Organic Synthesis   [0228] 
On the origin of cancer cells   [0231] 
Otto Warburg's contributions to current concepts of cancer metabolism   [0231] 
The SLC16 gene family - structure, role and regulation in health and disease   [0231] 
Blocking lactate export by inhibiting the myc target MCT1 disables glycolysis and glutathione synthesis   [0231] 
The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism   [0231] 
The interplay between MYC and HIF in the Warburg effect   [0231] 
Hypoxia in cancer: significance and impact on clinical outcome   [0231] 
Tumor hypoxia: a target for selective cancer therapy   [0231] 
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors   [0231] 
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice   [0231] 
Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH   [0231] 
The kinetics, substrate, and inhibitor specificity of the monocarboxylate (lactate) transporter of rat liver cells determined using the fluorescent intracellular pH indicator, 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein   [0231] 
mechanism of L-lactic acid transport in L6 skeletal muscle cells   [0231] 
Flavonoids modulate monocarboxylate transporter-1-mediated transport of γ-hydroxybutyrate in vitro and in vivo   [0231] 
Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells   [0231] 
Synthesis and Structure-Activity Relationships of Pteridine Dione and Trione Monocarboxylate Transporter 1 Inhibitors   [0231] 
Monocarboxylate transporter MCT1 is a target for immunosuppression   [0231] 
Potent blockers of the monocarboxylate transporter MCT1: novel immunomodulatory compounds   [0231] 
Optimization of monocarboxylate transporter 1 blockers through analysis and modulation of atropisomer interconversion properties   [0231] 
The specific monocarboxylate transporter (MCT1) inhibitor, AR-C117977, a novel immunosuppressant, prolongs allograft survival in the mouse   [0231] 
AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10   [0231] 
Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer   [0231] 
Novel Inhibitors of the Nuclear Factor of Activated T Cells (NFAT)-Mediated Transcription of .beta.-Galactosidase: Potential Immunosuppressive and Antiinflammatory Agents   [0231] 
Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells   [0231] 
Expression and distribution of lactate/monocarboxylate transporter isoforms in pancreatic islets and the exocrine pancreas   [0231] 
Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing   [0231] 
Physical exercise-induced hyperinsulinemic hypoglycemia is an autosomal-dominant trait characterized by abnormal pyruvate-induced insulin release   [0231] 
Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic beta-Cells Leads to Relative Hyperinsulinism During Exercise   [0231] 
Effects of lactate on pancreatic islets: Lactate efflux as a possible determinant of islet-cell depolarization by glucose   [0231] 
Flavonoids Modulate Monocarboxylate Transporter-1-Mediated Transport of gamma-Hydroxybutyrate in Vitro and in Vivo   [0231] 
Pharmacokinetic Interaction between the Flavonoid Luteolin and Gamma-Hydroxybutyrate in Rats: Potential Involvement of Monocarboxylate Transporters   [0231]