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Nature   [0008] 
Annual Rev. Immunol.   [0008] 
Proc. Nat'l. Acad. Sci. USA   [0010] 
CANCER RESEARCH   [0013] 
LEUKEMIA   [0014] 
Molecular Cloning: A Laboratory Manual   [0019] 
ANTIBODY PRODUCTION: ESSENTIAL TECHNIQUES   [0041] 
MONOCLONAL ANTIBODIES   [0041] 
MONOCLONAL ANTIBODIES: PRINCIPLES AND PRACTICE   [0041] 
CURRENT PROTOCOLS IN IMMUNOLOGY   [0041] 
Mol. Immunol.   [0041] 
ANTIBODY ENGINEERING: A PRACTICAL APPROACH   [0041]  [0076] 
Nature   [0042] 
Science   [0042] 
Proc. Natl. Acad. Sci. USA   [0042] 
Nature   [0049] 
Science   [0049] 
Proc. Natl. Acad. Sci. U.S.A.   [0049] 
J. Immunol.   [0049] 
Proc. Natl. Acad. Sci. USA   [0050] 
Sequences of Proteins of Immunological Interest   [0058] 
JMB   [0058] 
J. Mol. Biol.   [0058] 
Antibody-antigen interactions: Contact analysis and binding site topography   [0058] 
IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains   [0058] 
Yet another numbering scheme for immunoglobulin variable domains: an automatic modeling and analysis tool   [0058] 
MOLECULAR BIOLOGY OF THE GENE   [0061] 
Biochemistry   [0061] 
PNAS   [0061] 
J Biol Chem   [0061] 
Proc. Natl. Acad. Sci. USA   [0064] 
Nat Rev Cancer   [0065]  [0334]  [0334] 
Oncogene   [0065] 
Blood   [0065]  [0334] 
Leukemia   [0065] 
Comput. Appi. Biosci.   [0071] 
J. Mol. Biol.   [0071] 
Immunol. Today   [0075] 
MONOCLONAL ANTIBODIES AND CANCER THERAPY   [0075] 
J. Mol. Biol.   [0075] 
Adv. Drug Del. Rev.   [0075] 
J. Exp. Med.   [0075] 
Proc. Nat'l Acad. Sci. USA   [0076] 
Nat. Biotechnol   [0079] 
Nature   [0085]  [0086] 
Nature   [0085]  [0086] 
J. Mol. Biol.   [0085]  [0086] 
THE PHARMACOLOGY OF MONOCLONAL ANTIBODIES   [0094] 
Antibodies: A Laboratory Manual   [0101] 
Antibodies   [0101] 
Ann. Rev. Immunol.   [0102] 
Proc. Natl. Acad. Sci. U.S.A.   [0103] 
J. Mol. Biol.   [0103] 
Nature   [0103] 
Int. J. Pept. Protein Res.   [0103] 
Protein Engineering   [0103] 
Nature   [0105] 
Nature   [0105] 
Science   [0105] 
Proc. Natl. Acad. Sci. USA   [0105] 
J. Immunol.   [0105] 
Nature   [0107] 
Proc. Natl. Acad. Sci. USA   [0108] 
Nature Genetics   [0111] 
Curr. Opin. Biotechnol   [0111] 
Cancer Res.   [0127] 
Heterogeneity of Monoclonal Antibodies   [0132] 
Determination of the Origin of the N-Terminal Pyro-Glutamtate Variation in Monoclonal Antibodies Using Model Peptides   [0133] 
Anticancer Research   [0164] 
Adv. Drg Del. Rev.   [0164] 
Lancet   [0164] 
Antibody Carriers Of Cytotoxic Agents In Cancer Therapy: A Review   [0164] 
Cancer Immunol. Immunother.   [0164] 
Jour. of the Nat. Cancer Inst.   [0164] 
Bioorganic & Med. Chem. Letters   [0164] 
Bioconjugate Chem.   [0164] 
Proc. Natl. Acad. Sci. USA   [0164]  [0180] 
Cancer Res.   [0164] 
Cancer Res.   [0164] 
Eur. Jour. Nucl. Med.   [0165] 
Blood   [0165] 
J. Clin. Oncol.   [0165] 
J. Clin. Oncol.   [0165] 
Drugs of the Future   [0166] 
Proc Amer Assoc Cancer Res   [0167]  [0415] 
Nature Biotechnology   [0173] 
Science   [0175] 
PNAS   [0177] 
Cancer Research   [0180] 
Antimicrob. Agents and Chemothe   [0181] 
Antimicrob. Agents Chemother   [0181] 
Proceedings of the American Association for Cancer Research   [0182] 
The Peptides   [0183] 
J. Am. Chem. Soc.   [0183] 
Anti-Cancer Drug Design   [0183] 
Synthesis   [0183] 
J. Chem. Soc. Perkin Trans.   [0183] 
Nat Biotechnol   [0183] 
Cancer Research   [0184] 
Cancer Research   [0184] 
Biochem. Biophys. Res. Commun.   [0189] 
Monoclonal Antibodies in Immunoscintigraphy   [0189] 
Pharm. Therapeutics   [0202]  [0203] 
Biol. Chem.   [0203] 
Cancer Res.   [0204] 
Immunoconjugates: Antibody Conjugates in Radioimagery and Therapy of Cancer   [0204] 
J. Org. Chem.   [0217] 
Nature Biotechnology   [0217] 
Bioorg. Med. Chem. Lett.   [0218] 
Chemistry Biology   [0218] 
J. Amer. Chem. Soc.   [0218] 
J. Org. Chem.   [0218] 
J. Med. Chem.   [0218] 
Cancer Res   [0224] 
Pharmaceutical Salts   [0258] 
J. Org. Chem.   [0265] 
J. Org. Chem.   [0266] 
Effect of drug loading on the pharmacology, pharmacokinetics, and toxicity of an anti-CD30 antibody-drug conjugate   [0283] 
Proceedings of the AACR   [0283]  [0283] 
Controlling the location ofdrug attachment in antibody-drug conjugates   [0283] 
Intl. J. Oncology   [0287] 
J. Natl. Cancer Inst.   [0287] 
J. Immunol. Methods   [0288] 
Roche Molecular Biochemicals   [0289] 
Current Protocols in Immunology   [0290] 
Cancer Research   [0291] 
Nature Medicine   [0292] 
Remington's Pharmaceutical Sciences   [0294] 
Blood   [0308] 
Crit. Rev. Immunol.   [0310] 
Blood   [0310] 
Blood   [0310] 
Cancer Res.   [0310] 
J. Immunother. Emphasis Tumor Immunol   [0310] 
Leuk. Res.   [0310] 
Cancer Res.   [0310] 
Cancer Res.   [0310] 
J. Clin. Immunol.   [0310] 
Cancer Res.   [0311] 
International J. of Onco.   [0311] 
Cancer Res.   [0311] 
Oncogene   [0334] 
Leukemia   [0334] 
Mom Cancer Ther   [0334] 
Clin Cancer Res.   [0383] 
Eur J Cancer Clin Oncol.   [0383] 
Blood   [0415]