Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
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Perspectives in the treatment of pancreatic adenocarcinoma
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Inhibition of Ras for cancer treatment: the search continues
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Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance
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Modeling targeted inhibition of MEK and PI3 kinase in human pancreatic cancer
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Nature
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Mol.Cell. Therapeutics
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Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer
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Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas
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Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor beta signaling
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TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF-mutant melanoma
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Coffee EM, Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models
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1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites
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STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis
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Pancreatic cancer
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Pancreatic cancer-associated stroma production
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Complex role for the immune system in initiation and progression of pancreatic cancer
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The immune network in pancreatic cancer development and progression
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Pro-inflammatory cytokine release by peripheral blood mononuclear cells from patients with advanced pancreatic cancer: relationship to acute phase response and survival
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The desmoplastic stroma plays an essential role in the accumulation and modulation of infiltrated immune cells in pancreatic adenocarcinoma
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Target therapies in pancreatic carcinoma
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Metastatic pancreatic cancer: Is there a light at the end of the tunnel?
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Understanding metastasis in pancreatic cancer: a call for new clinical approaches
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Inflammatory networks and immune surveillance of pancreatic carcinoma
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Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy
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Distribution and clinical significance of tumour-associated macrophages in pancreatic ductal adenocarcinoma: a retrospective analysis in China
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Tumor-associated macrophages: from mechanisms to therapy
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Therapeutic vaccines for cancer: an overview of clinical trials
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Combination immunotherapy approaches
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Gaudernack G, Long-term follow-up of patients with resected pancreatic cancer following vaccination against mutant K-ras
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Understanding local macrophage phenotypes in disease: modulating macrophage function to treat cancer
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Adv. Enzyme Regul.
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New Avenues in Developmental Cancer Chemotherapy
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Molecular Systems Biology
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Remington's Pharmaceutical Sciences
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Systematic discovery of multicomponent therapeutics
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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
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Antitumor activity of targeted and cytotoxic agents in murine subcutaneous tumor models correlates with clinical response
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R Development Core Team
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Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer
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Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells
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STAT3 mediates resistance to MEK inhibitor through microRNA miR-17
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