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JP2006126073A   [0004] 
WO2012002460A   [0004] 

Biophys. J.   [0035] 
Mol. Pharmacol.   [0035] 
Proc. Natl. Acad. Sci. USA   [0035] 
Proc. Natl. Acad. Sci. USA   [0035] 
J. Gen. Physiol.   [0035] 
Circ. Res.   [0043] 
Am. J. Physiol. Cell Physiol.   [0043] 
J. Biol. Chem.   [0044] 
EMBO J.   [0045] 
Neuroscience.   [0046] 
J. Pharmacol. Exp. Ther.   [0046] 
J. Appl. Physiol.   [0046] 
Cell Biochem. Biophys.   [0047] 
Cardiovasc. Res.   [0053] 
J. Physiol.   [0053] 
Am J Physiol Cell Physiol   [0102] 
EMBO J.   [0103] 
Traffic   [0104] 
Chem Med Chem.   [0105] 
Bioorg Med Chem Lett.   [0106] 
Probe Reports from the NIH Molecular Libraries Program   [0106] 
Mechanism of Ba2+ block of a mouse inwardly rectifying K+ channel: differential contribution by two discrete residues   [0115] 
TREK-1, a K+ channel involved in polymodal pain perception   [0115] 
Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact   [0115] 
Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel   [0115] 
Targeting two-pore domain K+ channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept   [0115] 
O2 sensing by recombinant TWIK-related halothane-inhibitable K+ channel-1 background K+ channels heterologously expressed in human embryonic kidney cells   [0115] 
A unique role for the S4 segment of domain 4 in the inactivation of sodium channels   [0115] 
The selectivity filter may act as the agonist-activated gate in the G protein-activated K i r 3.1/K i r 3.4 K+ channel   [0115] 
Discovery of a pharmacologically active antagonist of the two-pore-domain potassium channel K2P9.1 (TASK-3)   [0115] 
Activation of TREK-1 by morphine results in analgesia without adverse side effects   [0115] 
Unique K i r 2.x properties determine regional and species differences in the cardiac inward rectifier K+ current   [0115] 
Alterations in gene expression in the caput epididymides of nonobstructive azoospermic men   [0115] 
The CNS under pathophysiologic attack--examining the role of K2P channels   [0115] 
Molecular background of leak K+ currents: two-pore domain potassium channels   [0115] 
Properties, regulation, pharmacology, and functions of the K2P channel, TRESK   [0115] 
Research into the therapeutic roles of two-pore-domain potassium channels   [0115] 
Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold   [0115] 
The TREK K2P channels and their role in general anaesthesia and neuroprotection   [0115] 
Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder   [0115] 
Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells   [0115] 
TREK-1, a K+ channel involved in neuroprotection and general anesthesia   [0115] 
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype   [0115] 
The neuronal background K2P channels: focus on TREK1   [0115] 
TASK-3, a new member of the tandem pore K+ channel family   [0115] 
Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5)   [0115] 
A TASK-like pH- and amine-sensitive 'leak' K+ conductance regulates neonatal rat facial motoneuron excitability in vitro   [0115] 
Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K+ channel   [0115] 
Biophysical, pharmacological, and functional characteristics of cloned and native mammalian two-pore domain K+ channels   [0115] 
External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter   [0115] 
TREK-1 is a heat-activated background K+ channel   [0115] 
Anorexic effect of K+ channel blockade in mesenteric arterial smooth muscle and intestinal epithelial cells   [0115] 
An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels   [0115] 
The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception   [0115] 
TWIK-2 channel deficiency leads to pulmonary hypertension through a rho-kinase-mediated process   [0115] 
Amino acid residues required for fast Na+-channel inactivation: charge neutralizations and deletions in the III-IV linker   [0115] 
The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1   [0115] 
Cloning, functional characterization, and remodeling of K2P3.1 (TASK-1) potassium channels in a porcine model of atrial fibrillation and heart failure   [0115] 
Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation   [0115] 
Barium block of K i r 2 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents   [0115] 
Molecular determinants of KATP channel inhibition by ATP   [0115] 
A cluster of hydrophobic amino acid residues required for fast Na-channel inactivation   [0115] 
Contribution of Kir2 potassium channels to ATP-induced cell death in brain capillary endothelial cells and reconstructed HEK293 cell model   [0115] 
ML365: Development of Bis-Amides as Selective Inhibitors of the KCNK3/TASK1 Two Pore Potassium Channel   [0115]